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The intramucosal distribution of gastric alcohol dehydrogenase and aldehyde dehydrogenase activity in rats.
Journal article

The intramucosal distribution of gastric alcohol dehydrogenase and aldehyde dehydrogenase activity in rats.

  • 1992-12-01
Published in:
  • Histochemistry. - 1992
Alcohol Dehydrogenase
Aldehyde Dehydrogenase
Animals
Female
Gastric Mucosa
Histocytochemistry
Kinetics
Male
Rats
Rats, Wistar
Sex Characteristics
Staining and Labeling
English Using qualitative and microquantitative histo-chemical techniques, alcohol dehydrogenase and aldehyde dehydrogenase activity was studied in the gastric mucosa of male and female rats. Alcohol dehydrogenase was demonstrated by staining reactions with maximum activity in surface and neck cells and with clearly weaker activity also in parietal cells. Aldehyde dehydrogenase could be detected in surface and neck cells, and also to a comparable degree in the parietal cells. Quantitative analyses of microdissected samples yielded high values for alcohol dehydrogenase activity exclusively in the superficial part of the gastric mucosa, whereas low-Km aldehyde dehydrogenase activity showed a decreasing gradient from the surface to the deeper parts of the mucosa. Sex differences could not be confirmed.
Language
  • English
Open access status
closed
Identifiers
Persistent URL
https://sonar.ch/global/documents/233015
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