How Anesthetic, Analgesic and Other Non-Surgical Techniques During Cancer Surgery Might Affect Postoperative Oncologic Outcomes: A Summary of Current State of Evidence.
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Forget P
Anesthesiology and Perioperative Medicine, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Laarbeeklaan 101, 1090 Brussels, Belgium. forgetpatrice@yahoo.fr.
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Aguirre JA
Anesthesiology, Balgrist University Hospital Zurich, 8091 Zurich, Switzerland. jose.aguirre@balgrist.ch.
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Bencic I
University Hospital for Tumors, Sestre Milosrdnice University Hospital Center, Zagreb 10000, Croatia. ivanka.bencic@gmail.com.
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Borgeat A
Anesthesiology, Balgrist University Hospital Zurich, 8091 Zurich, Switzerland. alain.borgeat@balgrist.ch.
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Cama A
Department of Pharmacy, Unit of General Pathology, Center on Aging Sciences and Translational Medicine (CeSI-MeT), "G. d'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy. alessandro.cama@unich.it.
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Condron C
Department of Surgery, Royal College of Surgeons in Ireland, Beaumont Hospital, 9 Dublin, Ireland. ccondron@rcsi.ie.
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Eintrei C
Department of Anesthesiology and Intensive Care, University of Linköping, 581 83 Linköping, Sweden. christina.eintrei@liu.se.
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Eroles P
INCLIVA Biomedical Research Institute, 46010 Valencia, Spain. pilar.eroles@uv.es.
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Gupta A
Physiology and Pharmacology, Karolinska Institutet, Perioperative Medicine and Intensive Care, Karolinska Hospital, 171 76 Stockholm, Sweden. Anil.gupta@sll.se.
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Hales TG
Division of Systems Medicine, School of Medicine, University of Dundee, Dundee DD1 9SY, UK. t.g.hales@dundee.ac.uk.
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Ionescu D
Head Department of Anesthesia and Intensive Care, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania, Outcome Research Consortium, Cleveland, OH 44195, USA. dionescuati@yahoo.com.
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Johnson M
Department of Anesthesia, Fiona Stanley Hospital, Perth, Western Australia. University College Dublin School of Medicine and Medical Science, 4 Dublin, Ireland. markzjohnson@gmail.com.
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Kabata P
Department of Surgical Oncology, Medical University of Gdańsk, 80-210 Gdańsk, Poland. pawel.kabata@gmail.com.
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Kirac I
Surgical Oncology, University Hospital for Tumors, Sestre Milosrdnice University Hospital Center, Zagreb 10000, Croatia. iva.kirac@kbcsm.hr.
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Ma D
Anesthetics, Pain Medicine & Intensive Care, Department of Surgery and Cancer, Imperial College London, Chelsea & Westminster Hospital, London SW10 9NH, UK. d.ma@imperial.ac.uk.
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Mokini Z
San Gerardo University Hospital, Monza, Italy. Clinique Saint Francois, 36000 Chateauroux, France. zheri@hotmail.com.
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Guerrero Orriach JL
Institute of Biomedical Research in Malaga [IBIMA], Department of Cardio-Anaesthesiology, Virgen de la Victoria University Hospital, 2010 Malaga, Spain. guerreroorriach@gmail.com.
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Retsky M
Department of Environmental Health, Harvard TH Chan School of Public Health, Boston, MA 02115, USA. michael.retsky@gmail.com.
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Sandrucci S
Visceral Sarcoma Unit, CDSS-University of Turin, 10124 Turin, Italy. sergio.sandrucci@unito.it.
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Siekmann W
Department of Anesthesiology and Intensive Care, Örebro University, 702 81 Örebro, Sweden. wiebke.siekmann@regionorebrolan.se.
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Štefančić L
Intensive Care Unit, University Hospital for Tumors, Sestre Milosrdnice University Hospital Center, Zagreb 10000, Croatia. lstefancic58@gmail.com.
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Votta-Vellis G
Departments of Anesthesiology and Surgery, College of Medicine, University of Illinois at Chicago, Chicago, IL 60607, USA. ginavot@uic.edu.
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Connolly C
Mater Misericordiae University Hospital, Eccles st., D07 R2WY Dublin, Ireland. caraconnolly83@gmail.com.
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Buggy D
Mater University Hospital, School of Medicine, University College Dublin, 4 Dublin, Ireland. donal.buggy@ucd.ie.
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English
The question of whether anesthetic, analgesic or other perioperative intervention during cancer resection surgery might influence long-term oncologic outcomes has generated much attention over the past 13 years. A wealth of experimental and observational clinical data have been published, but the results of prospective, randomized clinical trials are awaited. The European Union supports a pan-European network of researchers, clinicians and industry partners engaged in this question (COST Action 15204: Euro-Periscope). In this narrative review, members of the Euro-Periscope network briefly summarize the current state of evidence pertaining to the potential effects of the most commonly deployed anesthetic and analgesic techniques and other non-surgical interventions during cancer resection surgery on tumor recurrence or metastasis.
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Language
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Open access status
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gold
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Persistent URL
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https://sonar.ch/global/documents/236821
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