Common oral diseases in allogeneic haematopoietic stem cell transplantation (HSCT) recipients pre-HSCT.
- Uutela P Department of Oral Health & Medicine, University Center for Dental Medicine Basel, University of Basel, Basel, Switzerland.
- Passweg J Department of Hematology, University Hospital Basel, Basel, Switzerland.
- Halter J Department of Hematology, University Hospital Basel, Basel, Switzerland.
- Weiger R Department of Periodontology, Endodontology and Cariology, University Center for Dental Medicine Basel, University of Basel, Basel, Switzerland.
- Waltimo T Department of Oral Health & Medicine, University Center for Dental Medicine Basel, University of Basel, Basel, Switzerland.
- Mauramo M Department of Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
- 2019-01-12
Published in:
- European journal of haematology. - 2019
DMFT
caries
haematology
periodontitis
stem cell transplantation
Adult
Case-Control Studies
Female
Hematologic Neoplasms
Hematopoietic Stem Cell Transplantation
Humans
Male
Middle Aged
Mouth Diseases
Transplantation, Homologous
Young Adult
English
OBJECTIVES
The purpose of this study was to compare the prevalence of common oral diseases between allogeneic haematopoietic stem cell transplantation (HSCT) recipients and healthy controls.
MATERIALS AND METHODS
A total of 143 adult allogeneic HSCT recipients who were treated for haematological malignancies between 2008 and 2016 were included in the study. The HSCT recipients were age and sex matched with healthy controls. A dental examination was performed on the HSCT recipients prior to HSCT. Differences in stimulated saliva flow rate (SSFR), decayed, missing and filled teeth (DMFT) index, number of teeth, number of caries lesions, and measures of current or previous periodontitis (radiological attachment loss >3 mm or probing pocket depth ≥4 mm) between HSCT recipients and controls were examined.
RESULTS
Stimulated saliva flow rate, DMFT index and the number of caries lesions were poorer in the HSCT recipients pre-HSCT compared to controls (all P-values <0.05). No statistically significant differences in the measures of current or previous periodontitis were observed.
CONCLUSIONS
Stimulated saliva flow rate was low and caries was common in HSCT recipients prior to HSCT. Efficient preventive strategies are important in order to maintain the oral health of these patients.
The purpose of this study was to compare the prevalence of common oral diseases between allogeneic haematopoietic stem cell transplantation (HSCT) recipients and healthy controls.
MATERIALS AND METHODS
A total of 143 adult allogeneic HSCT recipients who were treated for haematological malignancies between 2008 and 2016 were included in the study. The HSCT recipients were age and sex matched with healthy controls. A dental examination was performed on the HSCT recipients prior to HSCT. Differences in stimulated saliva flow rate (SSFR), decayed, missing and filled teeth (DMFT) index, number of teeth, number of caries lesions, and measures of current or previous periodontitis (radiological attachment loss >3 mm or probing pocket depth ≥4 mm) between HSCT recipients and controls were examined.
RESULTS
Stimulated saliva flow rate, DMFT index and the number of caries lesions were poorer in the HSCT recipients pre-HSCT compared to controls (all P-values <0.05). No statistically significant differences in the measures of current or previous periodontitis were observed.
CONCLUSIONS
Stimulated saliva flow rate was low and caries was common in HSCT recipients prior to HSCT. Efficient preventive strategies are important in order to maintain the oral health of these patients.
- Language
-
- English
- Open access status
- green
- Identifiers
-
- DOI 10.1111/ejh.13209
- PMID 30632215
- Persistent URL
- https://sonar.ch/global/documents/238361
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