Cancer mortality in Europe in 2015 and an overview of trends since 1990.
- Bertuccio P Departments of Biomedical and Clinical Sciences, Università degli Studi di Milano, Milan.
- Alicandro G Clinical Sciences and Community Health, Università degli Studi di Milano, Milan; Directorate for Social Statistics and Population Census, Italian National Institute of Statistics (ISTAT), Rome, Italy.
- Malvezzi M Clinical Sciences and Community Health, Università degli Studi di Milano, Milan.
- Carioli G Clinical Sciences and Community Health, Università degli Studi di Milano, Milan.
- Boffetta P Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, USA; Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.
- Levi F Institute of Social and Preventive Medicine (IUMSP), Lausanne University Hospital, Lausanne, Switzerland.
- La Vecchia C Clinical Sciences and Community Health, Università degli Studi di Milano, Milan. Electronic address: carlo.lavecchia@unimi.it.
- Negri E Departments of Biomedical and Clinical Sciences, Università degli Studi di Milano, Milan.
- 2019-06-01
Published in:
- Annals of oncology : official journal of the European Society for Medical Oncology. - 2019
Europe
cancer
mortality
trends
Adolescent
Adult
Age Distribution
Aged
Aged, 80 and over
Child
Child, Preschool
Databases, Factual
Europe
Female
Humans
Infant
Infant, Newborn
Male
Middle Aged
Mortality
Neoplasms
Public Policy
Sex Factors
Smoking Prevention
Tobacco Smoking
World Health Organization
Young Adult
English
BACKGROUND
Cancer mortality in Europe has been decreasing since the late 1980s or 1990s in some countries with different patterns in many areas. In this study, we updated trends in cancer mortality in Europe.
MATERIALS AND METHODS
We extracted data from the World Health Organization mortality database for 24 cancer sites, 36 European countries and the European Union (EU) as a whole over the 1990-2017 period. We computed age-standardized death rates per 100 000 person-years, and we carried out a joinpoint regression analysis of mortality trends from all cancers and selected major neoplasms. The estimated annual percent change (APC) for each identified linear segment, and the weighted average APC (AAPC) over the entire study period were provided as summary measures of the changes in rates over the time period.
RESULTS
In 2015, the age-standardized mortality rates from all cancers in the EU were 137.5 deaths per 100 000 in men and 85.7 in women. Eastern European countries showed the highest rates with values over 150 deaths per 100 000 in men and over 100 deaths per 100 000 in women. Mortality from all cancers in the EU declined annually by 1.5% in men since 2006 and by 0.8% in women since 2007. Most cancer sites showed decreasing trends, with steady declines over the whole period for cancers of stomach, intestines, lung in men, breast and prostate. Unfavourable mortality trends persisted for cancers of liver, lung in women, pancreas, besides skin and kidney in men.
CONCLUSIONS
The downward trends in total cancer mortality in Europe still continue over the last decade. However, the trends were less favourable in most eastern European countries. Tobacco control in men (but not in women), improvements in diagnosis and therapy were the main underlying factors of these trends.
Cancer mortality in Europe has been decreasing since the late 1980s or 1990s in some countries with different patterns in many areas. In this study, we updated trends in cancer mortality in Europe.
MATERIALS AND METHODS
We extracted data from the World Health Organization mortality database for 24 cancer sites, 36 European countries and the European Union (EU) as a whole over the 1990-2017 period. We computed age-standardized death rates per 100 000 person-years, and we carried out a joinpoint regression analysis of mortality trends from all cancers and selected major neoplasms. The estimated annual percent change (APC) for each identified linear segment, and the weighted average APC (AAPC) over the entire study period were provided as summary measures of the changes in rates over the time period.
RESULTS
In 2015, the age-standardized mortality rates from all cancers in the EU were 137.5 deaths per 100 000 in men and 85.7 in women. Eastern European countries showed the highest rates with values over 150 deaths per 100 000 in men and over 100 deaths per 100 000 in women. Mortality from all cancers in the EU declined annually by 1.5% in men since 2006 and by 0.8% in women since 2007. Most cancer sites showed decreasing trends, with steady declines over the whole period for cancers of stomach, intestines, lung in men, breast and prostate. Unfavourable mortality trends persisted for cancers of liver, lung in women, pancreas, besides skin and kidney in men.
CONCLUSIONS
The downward trends in total cancer mortality in Europe still continue over the last decade. However, the trends were less favourable in most eastern European countries. Tobacco control in men (but not in women), improvements in diagnosis and therapy were the main underlying factors of these trends.
- Language
-
- English
- Open access status
- bronze
- Identifiers
-
- DOI 10.1093/annonc/mdz179
- PMID 31147719
- Persistent URL
- https://sonar.ch/global/documents/239267
Statistics
Document views: 10
File downloads:
- fulltext.pdf: 0