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Production of GPCR and GPCR complexes for structure determination.
Journal article

Production of GPCR and GPCR complexes for structure determination.

  • Maeda S Laboratory of Biomolecular Research, Paul Scherrer Institute, 5232 Villigen PSI, Switzerland.
  • Schertler GF
  • 2013-05-28
Published in:
  • Current opinion in structural biology. - 2013
Crystallization
Crystallography, X-Ray
Escherichia coli
Gene Expression
Humans
Protein Conformation
Receptors, G-Protein-Coupled
English Since the first high-resolution structure of the beta 2 adrenergic receptor (b2AR) in 2007, we have seen a growing number of G-protein-coupled receptor (GPCR) structures coming to the repertory, providing a significant progress in our understanding of the structural basis of their function. This has been achieved by the interdisciplinary collaborative work between scientists with various expertise and the development of new methodologies as well as combining and optimizing existing techniques.
Language
  • English
Open access status
closed
Identifiers
Persistent URL
https://sonar.ch/global/documents/239419
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