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Evidence-based review of the Bioenterics intragastric balloon for weight loss.

  • Dumonceau JM Division of Gastroenterology and Hepatology, Geneva University Hospitals, Micheli-du-Crest Street, 24, 1205 Geneva, Switzerland. Jean-Marc.Dumonceau@hcuge.ch
  • 2008-06-24
Published in:
  • Obesity surgery. - 2008
Body Mass Index
Comorbidity
Contraindications
Device Removal
Endoscopy, Gastrointestinal
Equipment Design
Gastric Balloon
Humans
Obesity, Morbid
Quality of Life
Treatment Outcome
Weight Loss
English We reviewed clinical studies performed with the Bioenterics intragastric balloon (BIB) to promote weight loss. Thirty studies were included [18 prospective (5 randomized), 12 retrospective], totaling 4,877 patients. Only one of three sham-controlled trials found a significantly higher weight loss with the BIB vs the sham procedure plus exhaustive follow-up. In nonrandomized studies, weight loss with the BIB averaged 17.8 kg (range, 4.9-28.5), corresponding to BMI changes of 4.0-9.0 kg/m(2). Comorbidities resolved or improved in 52-100% of patients. Best short-term results were observed in patients devoid of binge eating disorder with a BMI in the 30.0-40.0 kg/m(2) range; the BIB also helped to prepare superobese patients for bariatric surgery. Severe complications were exceptional (gastric perforation and intestinal obstruction; 0.2% each); digestive intolerance prompted early BIB removal in 2.5% of patients. Long-term (>or=2 years) results are awaited, as well as well-designed studies to define the best indications for this therapy.
Language
  • English
Open access status
green
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https://sonar.ch/global/documents/240146
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