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Enantioselective Chemo- and Biocatalysis: Partners in Retrosynthesis.
Journal article

Enantioselective Chemo- and Biocatalysis: Partners in Retrosynthesis.

  • Hönig M Laboratorium für Organische Chemie, Eidgenössische Technische Hochschule Zürich, Vladimir-Prelog-Weg 3, 8093, Zürich, Switzerland.
  • Sondermann P Laboratorium für Organische Chemie, Eidgenössische Technische Hochschule Zürich, Vladimir-Prelog-Weg 3, 8093, Zürich, Switzerland.
  • Turner NJ Manchester Institute of Biotechnology & School of Chemistry, University of Manchester, 131 Princess Street, Manchester, M1 7DN, UK.
  • Carreira EM Laboratorium für Organische Chemie, Eidgenössische Technische Hochschule Zürich, Vladimir-Prelog-Weg 3, 8093, Zürich, Switzerland.
  • 2017-04-14
Published in:
  • Angewandte Chemie (International ed. in English). - 2017
biocatalysis
catalysis
enantioselectivity
retrosynthesis
Acylation
Alcohols
Amination
Amines
Biocatalysis
Enzymes
Hydrolysis
Organic Chemicals
Oxidation-Reduction
Stereoisomerism
English Recent developments of stereoselective biocatalytic and chemocatalytic methods are discussed. The review provides a guide to the use of biocatalytic methods in the area of chemical synthesis with focused attention on retrosynthetic considerations and analysis. The transformations presented are organized according to bond disconnections and attendant synthetic methods. The review is expected to lead to better understanding of the characteristics and distinctions of the two complementary approaches. It depicts for researchers in bio- and chemocatalysis a road map of challenges and opportunities for the evolution (and at times revolution) in chemical synthesis.
Language
  • English
Open access status
closed
Identifiers
Persistent URL
https://sonar.ch/global/documents/241376
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