Journal article
3D-constructive interference into steady state (3D-CISS) labyrinth signal alteration in patients with vestibular schwannoma.
- Wagner F Department of Diagnostic and Interventional Neuroradiology, Inselspital, University of Bern, Bern, Switzerland. Electronic address: franca.wagner@insel.ch.
- Herrmann E Department of Radiation Oncology, Inselspital, University of Bern, Bern, Switzerland. Electronic address: evelyn.herrmann@insel.ch.
- Wiest R Department of Diagnostic and Interventional Neuroradiology, Inselspital, University of Bern, Bern, Switzerland. Electronic address: roland.wiest@insel.ch.
- Raabe A Department of Neurosurgery, Inselspital, University of Bern, Bern, Switzerland. Electronic address: andreas.raabe@insel.ch.
- Bernasconi C Statistics Division, Inselspital, University of Bern, Bern, Switzerland. Electronic address: corrado.bernasconi@insel.ch.
- Caversaccio M Department of Otorhinolaryngology and Head & Neck Surgery, Inselspital, University of Bern, Bern, Switzerland. Electronic address: marco.caversaccio@insel.ch.
- Vibert D Department of Otorhinolaryngology and Head & Neck Surgery, Inselspital, University of Bern, Bern, Switzerland. Electronic address: dominique.vibert@insel.ch.
- 2017-09-27
Published in:
- Auris, nasus, larynx. - 2018
3D-CISS
Labyrinth signal loss
MRI
Treatment
Vertigo
Vestibular schwannoma
Adult
Aged
Aged, 80 and over
Ear, Inner
Humans
Imaging, Three-Dimensional
Magnetic Resonance Imaging
Middle Aged
Neuroma, Acoustic
Otorhinolaryngologic Surgical Procedures
Radiosurgery
Saccule and Utricle
Vertigo
Watchful Waiting
Young Adult
English
OBJECTIVE
To evaluate signal intensity of the inner ear using 3D-CISS imaging and correlated signal characteristics in patients with vestibular schwannoma to neuro-otological symptoms.
METHODS
Sixty patients with unilateral vestibular schwannoma were retrospectively reviewed. All patients had had initial and follow-up magnetic resonance imaging (MRI). Individual treatment strategies consisted of "wait-and-watch", surgical tumour resection, stereotactic radiosurgery or both surgery and stereotactic radiosurgery. For all patients a complete baseline and treatment course neuro-otological examination was re-studied.
RESULTS
On initial MRI, 3D-CISS sequence signal loss of the membranous labyrinth was present in 20 patients (33.3%); signal loss of cochlea in 20 (33.3%) and coincident signal loss of sacculus/utriculus in 17 (85%) of them. Sequential analysis of follow-up MRI series demonstrated slightly increased labyrinthine signal degradation, independently of the chosen therapy. Correlation of initial MRI results with initial neuro-otological symptoms showed significance only for cochlear obstruction versus vertigo (p=0.0397) and sacculus/utriculus obstruction versus vertigo (p=0.0336). No other statistically significant relationships were noted.
CONCLUSION
3D-constructive interference into steady state (3D-CISS) is appropriate for observing inner ear signal loss in patients with vestibular schwannoma. However, except for vertigo, no significant correlation was noted between initial neuro-otological symptomatology and signal loss of the inner ear.
To evaluate signal intensity of the inner ear using 3D-CISS imaging and correlated signal characteristics in patients with vestibular schwannoma to neuro-otological symptoms.
METHODS
Sixty patients with unilateral vestibular schwannoma were retrospectively reviewed. All patients had had initial and follow-up magnetic resonance imaging (MRI). Individual treatment strategies consisted of "wait-and-watch", surgical tumour resection, stereotactic radiosurgery or both surgery and stereotactic radiosurgery. For all patients a complete baseline and treatment course neuro-otological examination was re-studied.
RESULTS
On initial MRI, 3D-CISS sequence signal loss of the membranous labyrinth was present in 20 patients (33.3%); signal loss of cochlea in 20 (33.3%) and coincident signal loss of sacculus/utriculus in 17 (85%) of them. Sequential analysis of follow-up MRI series demonstrated slightly increased labyrinthine signal degradation, independently of the chosen therapy. Correlation of initial MRI results with initial neuro-otological symptoms showed significance only for cochlear obstruction versus vertigo (p=0.0397) and sacculus/utriculus obstruction versus vertigo (p=0.0336). No other statistically significant relationships were noted.
CONCLUSION
3D-constructive interference into steady state (3D-CISS) is appropriate for observing inner ear signal loss in patients with vestibular schwannoma. However, except for vertigo, no significant correlation was noted between initial neuro-otological symptomatology and signal loss of the inner ear.
- Language
-
- English
- Open access status
- closed
- Identifiers
-
- DOI 10.1016/j.anl.2017.09.011
- PMID 28947096
- Persistent URL
- https://sonar.ch/global/documents/241828
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