New genetic loci link adipose and insulin biology to body fat distribution.
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Shungin D
Department of Public Health and Clinical Medicine, Unit of Medicine, Umeå University, Umeå 901 87, Sweden.
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Winkler TW
Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, D-93053 Regensburg, Germany.
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Croteau-Chonka DC
Department of Genetics, University of North Carolina, Chapel Hill, NC 27599, USA.
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Ferreira T
Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.
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Locke AE
Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA.
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Mägi R
Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.
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Strawbridge RJ
Atherosclerosis Research Unit, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm 17176, Sweden.
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Pers TH
Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA 02115, USA.
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Fischer K
Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.
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Justice AE
Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
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Workalemahu T
Department of Nutrition, Harvard School of Public Health, Boston, MA, USA.
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Wu JMW
Department of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA.
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Buchkovich ML
Department of Genetics, University of North Carolina, Chapel Hill, NC 27599, USA.
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Heard-Costa NL
National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham MA 01702, USA.
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Roman TS
Department of Genetics, University of North Carolina, Chapel Hill, NC 27599, USA.
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Drong AW
Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.
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Song C
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm 17177, Sweden.
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Gustafsson S
Science for Life Laboratory, Uppsala University, Uppsala 75185, Sweden.
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Day FR
MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK.
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Esko T
Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.
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Fall T
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm 17177, Sweden.
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Kutalik Z
Institute of Social and Preventive Medicine (IUMSP), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne 1010, Switzerland.
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Luan J
MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK.
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Randall JC
Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.
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Scherag A
Institute for Medical Informatics, Biometry and Epidemiology (IMIBE), University Hospital Essen, Essen, Germany.
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Vedantam S
Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA 02115, USA.
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Wood AR
Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter EX1 2LU, UK.
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Chen J
Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI, USA.
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Fehrmann R
Department of Genetics, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.
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Karjalainen J
Department of Genetics, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.
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Kahali B
Department of Internal Medicine, Division of Gastroenterology, and Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109.
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Liu CT
Department of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA.
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Schmidt EM
Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.
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Absher D
HudsonAlpha Institute for Biotechnology, Huntsville, AL 35806, USA.
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Amin N
Genetic Epidemiology Unit, Department of Epidemiology, Erasmus MC University Medical Center, 3015 GE Rotterdam, The Netherlands.
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Anderson D
Telethon Institute for Child Health Research, Centre for Child Health Research, The University of Western Australia, Perth, Western Australia 6008, Australia.
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Beekman M
Netherlands Consortium for Healthy Aging (NCHA), Leiden University Medical Center, Leiden 2300 RC, The Netherlands.
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Bragg-Gresham JL
Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA.
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Buyske S
Department of Statistics & Biostatistics, Rutgers University, Piscataway, NJ USA.
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Demirkan A
Genetic Epidemiology Unit, Department of Epidemiology, Erasmus MC University Medical Center, 3015 GE Rotterdam, The Netherlands.
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Ehret GB
Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
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Feitosa MF
Department of Genetics, Washington University School of Medicine, St. Louis, MO 63110, USA.
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Goel A
Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.
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Jackson AU
Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA.
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Johnson T
Swiss Institute of Bioinformatics, Lausanne 1015, Switzerland.
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Kleber ME
Vth Department of Medicine (Nephrology, Hypertensiology, Endocrinology, Diabetology, Rheumatology), Medical Faculty of Mannheim, University of Heidelberg, Germany.
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Kristiansson K
National Institute for Health and Welfare, FI-00271 Helsinki, Finland.
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Mangino M
Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK.
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Leach IM
Department of Cardiology, University Medical Center Groningen, University of Groningen, 9700RB Groningen, The Netherlands.
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Medina-Gomez C
Netherlands Consortium for Healthy Aging (NCHA), 3015GE Rotterdam, The Netherlands.
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Palmer CD
Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA 02115, USA.
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Pasko D
Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter EX1 2LU, UK.
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Pechlivanis S
Institute for Medical Informatics, Biometry and Epidemiology (IMIBE), University Hospital Essen, Essen, Germany.
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Peters MJ
Netherlands Consortium for Healthy Aging (NCHA), 3015GE Rotterdam, The Netherlands.
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Prokopenko I
Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.
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Stančáková A
University of Eastern Finland, FI-70210 Kuopio, Finland.
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Sung YJ
Division of Biostatistics, Washington University School of Medicine, St. Louis, MO 63110, USA.
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Tanaka T
Translational Gerontology Branch, National Institute on Aging, Baltimore MD 21225, USA.
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Teumer A
Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, D-17475 Greifswald, Germany.
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Van Vliet-Ostaptchouk JV
Department of Endocrinology, University of Groningen, University Medical Center Groningen, Groningen, 9700 RB, The Netherlands.
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Yengo L
CNRS UMR 8199, F-59019 Lille, France.
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Zhang W
Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK.
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Albrecht E
Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.
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Ärnlöv J
Science for Life Laboratory, Uppsala University, Uppsala 75185, Sweden.
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Arscott GM
PathWest Laboratory Medicine of Western Australia, NEDLANDS, Western Australia 6009, Australia.
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Bandinelli S
Geriatric Unit, Azienda Sanitaria Firenze (ASF), Florence, Italy.
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Barrett A
Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford OX3 7LJ, UK.
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Bellis C
Department of Genetics, Texas Biomedical Research Institute, San Antonio, TX, USA.
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Bennett AJ
Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford OX3 7LJ, UK.
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Berne C
Department of Medical Sciences, Endocrinology, Diabetes and Metabolism, Uppsala University, Uppsala 75185, Sweden.
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Blüher M
Integrated Research and Treatment Center (IFB) Adiposity Diseases, University of Leipzig, D-04103 Leipzig, Germany.
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Böhringer S
Netherlands Consortium for Healthy Aging (NCHA), Leiden University Medical Center, Leiden 2300 RC, The Netherlands.
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Bonnet F
Inserm UMR991, Department of Endocrinology, University of Rennes, F-35000 Rennes, France.
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Böttcher Y
Integrated Research and Treatment Center (IFB) Adiposity Diseases, University of Leipzig, D-04103 Leipzig, Germany.
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Bruinenberg M
LifeLines Cohort Study, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.
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Carba DB
USC-Office of Population Studies Foundation, Inc., University of San Carlos, Cebu City 6000, Philippines.
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Caspersen IH
Department of Biology, Norwegian University of Science and Technology, Trondheim, Norway.
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Clarke R
Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford OX3 7LF, UK.
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Daw EW
Department of Genetics, Washington University School of Medicine, St. Louis, MO 63110, USA.
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Deelen J
Netherlands Consortium for Healthy Aging (NCHA), Leiden University Medical Center, Leiden 2300 RC, The Netherlands.
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Deelman E
Information Sciences Institute, University of Southern California, Marina del Rey, California, USA.
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Delgado G
Vth Department of Medicine (Nephrology, Hypertensiology, Endocrinology, Diabetology, Rheumatology), Medical Faculty of Mannheim, University of Heidelberg, Germany.
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Doney AS
Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK.
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Eklund N
National Institute for Health and Welfare, FI-00271 Helsinki, Finland.
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Erdos MR
Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, MD 20892, USA.
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Estrada K
Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge 02142, MA, USA.
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Eury E
CNRS UMR 8199, F-59019 Lille, France.
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Friedrich N
Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, D-17475 Greifswald, Germany.
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Garcia ME
Laboratory of Epidemiology and Population Sciences, National Institute on Aging, NIH, Bethesda, MD 20892, USA.
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Giedraitis V
Department of Public Health and Caring Sciences, Geriatrics, Uppsala University, Uppsala 75185, Sweden.
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Gigante B
Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden, Stockholm 17177, Sweden.
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Go AS
Kaiser Permanente, Division of Research, Oakland, CA 94612, USA.
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Golay A
Service of Therapeutic Education for Diabetes, Obesity and Chronic Diseases, Geneva University Hospital, Geneva CH-1211, Switzerland.
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Grallert H
Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.
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Grammer TB
Vth Department of Medicine (Nephrology, Hypertensiology, Endocrinology, Diabetology, Rheumatology), Medical Faculty of Mannheim, University of Heidelberg, Germany.
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Gräßler J
Department of Medicine III, University Hospital Carl Gustav Carus, Technische Universität Dresden, D-01307 Dresden, Germany.
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Grewal J
Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK.
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Groves CJ
Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford OX3 7LJ, UK.
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Haller T
Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.
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Hallmans G
Department of Public Health and Clinical Medicine, Unit of Nutritional Research, Umeå University, Umeå 90187, Sweden.
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Hartman CA
Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
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Hassinen M
Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.
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Hayward C
MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, EH4 2XU, Scotland, UK.
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Heikkilä K
Hjelt Institute Department of Public Health, University of Helsinki, FI-00014 Helsinki, Finland.
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Herzig KH
Institute of Biomedicine, University of Oulu, Oulu, Finland.
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Helmer Q
Netherlands Consortium for Healthy Aging (NCHA), Leiden University Medical Center, Leiden 2300 RC, The Netherlands.
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Hillege HL
Department of Cardiology, University Medical Center Groningen, University of Groningen, 9700RB Groningen, The Netherlands.
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Holmen O
Department of Public Health and General Practice, Norwegian University of Science and Technology, Trondheim 7489, Norway.
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Hunt SC
Cardiovascular Genetics Division, Department of Internal Medicine, University of Utah, Salt Lake City, Utah 84108, USA.
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Isaacs A
Genetic Epidemiology Unit, Department of Epidemiology, Erasmus MC University Medical Center, 3015 GE Rotterdam, The Netherlands.
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Ittermann T
Institute for Community Medicine, University Medicine Greifswald, D-17475 Greifswald, Germany.
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James AL
Department of Pulmonary Physiology and Sleep Medicine, Nedlands, Western Australia 6009, Australia.
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Johansson I
Department of Odontology, Umeå University, Umeå 901 85, Sweden.
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Juliusdottir T
Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.
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Kalafati IP
Department of Dietetics-Nutrition, Harokopio University, Athens, Greece.
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Kinnunen L
National Institute for Health and Welfare, FI-00271 Helsinki, Finland.
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Koenig W
Department of Internal Medicine II, Ulm University Medical Centre, D-89081 Ulm, Germany.
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Kooner IK
Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK.
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Kratzer W
Department of Internal Medicine I, Ulm University Medical Centre, D-89081 Ulm, Germany.
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Lamina C
Division of Genetic Epidemiology, Department of Medical Genetics, Molecular and Clinical Pharmacology, Innsbruck Medical University, 6020 Innsbruck, Austria.
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Leander K
Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden, Stockholm 17177, Sweden.
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Lee NR
USC-Office of Population Studies Foundation, Inc., University of San Carlos, Cebu City 6000, Philippines.
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Lichtner P
Institute of Human Genetics, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.
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Lind L
Department of Medical Sciences, Cardiovascular Epidemiology, Uppsala University, Uppsala 75185, Sweden.
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Lindström J
National Institute for Health and Welfare, FI-00271 Helsinki, Finland.
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Lobbens S
CNRS UMR 8199, F-59019 Lille, France.
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Lorentzon M
Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg 413 45, Sweden.
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Mach F
Cardiology, Department of Specialties of Internal Medicine, Geneva University Hospital, Geneva 1211, Switzerland.
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Magnusson PK
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm 17177, Sweden.
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Mahajan A
Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.
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McArdle WL
School of Social and Community Medicine, University of Bristol, Bristol BS8 2BN, UK.
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Menni C
Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK.
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Merger S
Division of Endocrinology, Diabetes and Metabolism, Ulm University Medical Centre, D-89081 Ulm, Germany.
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Mihailov E
Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.
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Milani L
Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.
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Mills R
Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK.
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Moayyeri A
Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK.
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Monda KL
Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
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Mooijaart SP
Netherlands Consortium for Healthy Aging (NCHA), Leiden University Medical Center, Leiden 2300 RC, The Netherlands.
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Mühleisen TW
Department of Genomics, Life & Brain Center, University of Bonn, Bonn, Germany.
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Mulas A
Istituto di Ricerca Genetica e Biomedica (IRGB), Consiglio Nazionale delle Ricerche, Cagliari, Sardinia 09042, Italy.
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Müller G
Center for Evidence-based Healthcare, University Hospital Carl Gustav Carus, Technische Universität Dresden, D-01307 Dresden, Germany.
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Müller-Nurasyid M
Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.
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Nagaraja R
Laboratory of Genetics, National Institute on Aging, Baltimore, MD 21224, USA.
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Nalls MA
Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD 20892, USA.
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Narisu N
Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, MD 20892, USA.
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Glorioso N
Hypertension and Related Diseases Centre - AOU, University of Sassari Medical School, Sassari 07100, Italy.
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Nolte IM
Department of Epidemiology, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.
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Olden M
Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, D-93053 Regensburg, Germany.
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Rayner NW
Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.
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Renstrom F
Department of Clinical Sciences, Genetic & Molecular Epidemiology Unit, Lund University Diabetes Center, Skåne University Hosptial, Malmö 205 02, Sweden.
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Ried JS
Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.
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Robertson NR
Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.
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Rose LM
Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA 02215, USA.
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Sanna S
Istituto di Ricerca Genetica e Biomedica (IRGB), Consiglio Nazionale delle Ricerche, Cagliari, Sardinia 09042, Italy.
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Scharnagl H
Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz 8036, Austria.
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Scholtens S
LifeLines Cohort Study, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.
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Sennblad B
Atherosclerosis Research Unit, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm 17176, Sweden.
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Seufferlein T
Department of Internal Medicine I, Ulm University Medical Centre, D-89081 Ulm, Germany.
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Sitlani CM
Department of Medicine, University of Washington, Seattle, WA 98101, USA.
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Smith AV
Icelandic Heart Association, Kopavogur 201, Iceland.
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Stirrups K
Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.
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Stringham HM
Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA.
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Sundström J
Department of Medical Sciences, Cardiovascular Epidemiology, Uppsala University, Uppsala 75185, Sweden.
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Swertz MA
Department of Genetics, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.
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Swift AJ
Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, MD 20892, USA.
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Syvänen AC
Science for Life Laboratory, Uppsala University, Uppsala 75185, Sweden.
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Tayo BO
Department of Public Health Sciences, Stritch School of Medicine, Loyola University of Chicago, Maywood, IL 61053, USA.
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Thorand B
German Center for Diabetes Research (DZD), Neuherberg, Germany.
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Thorleifsson G
deCODE Genetics, Amgen inc., Reykjavik 101, Iceland.
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Tomaschitz A
Department of Cardiology, Medical University of Graz, Graz 8036, Austria.
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Troffa C
Hypertension and Related Diseases Centre - AOU, University of Sassari Medical School, Sassari 07100, Italy.
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van Oort FV
Department of Child and Adolescent Psychiatry, Psychology, Erasmus MC University Medical Centre, 3000 CB Rotterdam, The Netherlands.
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Verweij N
Department of Cardiology, University Medical Center Groningen, University of Groningen, 9700RB Groningen, The Netherlands.
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Vonk JM
Department of Epidemiology, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.
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Waite LL
HudsonAlpha Institute for Biotechnology, Huntsville, AL 35806, USA.
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Wennauer R
Department of Clinical Chemistry, Ulm University Medical Centre, D-89081 Ulm, Germany.
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Wilsgaard T
Department of Community Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø, Norway.
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Wojczynski MK
Department of Genetics, Washington University School of Medicine, St. Louis, MO 63110, USA.
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Wong A
MRC Unit for Lifelong Health and Ageing at University College London, London WC1B 5JU, UK.
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Zhang Q
Department of Genetics, Washington University School of Medicine, St. Louis, MO 63110, USA.
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Zhao JH
MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK.
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Brennan EP
Diabetes Complications Research Centre, Conway Institute, School of Medicine and Medical Sciences, University College Dublin, Dublin, Ireland.
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Choi M
Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Korea.
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Eriksson P
Atherosclerosis Research Unit, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm 17176, Sweden.
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Folkersen L
Atherosclerosis Research Unit, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm 17176, Sweden.
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Franco-Cereceda A
Cardiothoracic Surgery Unit, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm 17176, Sweden.
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Gharavi AG
Department of Medicine, Columbia University College of Physicians and Surgeons, New York NY, USA.
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Hedman ÅK
Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.
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Hivert MF
Department of Population Medicine, Harvard Pilgrim Health Care Institute, Harvard Medical School, Boston, MA.
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Huang J
State Key Laboratory of Medical Genomics, Shanghai Institute of Hematology, Rui Jin Hospital Affiliated with Shanghai Jiao Tong University School of Medicine, Shanghai, China.
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Kanoni S
William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, EC1M 6BQ UK.
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Karpe F
Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford OX3 7LJ, UK.
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Keildson S
Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.
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Kiryluk K
Department of Medicine, Columbia University College of Physicians and Surgeons, New York NY, USA.
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Liang L
Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA.
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Lifton RP
Department of Genetics, Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, New Haven CT, USA.
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Ma B
Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA.
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McKnight AJ
Nephrology Research, Centre for Public Health, Queen's University of Belfast, Belfast, Co. Down BT9 7AB, UK.
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McPherson R
University of Ottawa Heart Institute, Ottawa K1Y 4W7, Canada.
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Metspalu A
Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.
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Min JL
School of Social and Community Medicine, University of Bristol, Bristol BS8 2BN, UK.
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Moffatt MF
National Heart and Lung Institute, Imperial College London, London SW3 6LY, UK.
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Montgomery GW
QIMR Berghofer Medical Research Institute, Brisbane, Queensland 4006, Australia.
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Murabito JM
National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham MA 01702, USA.
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Nicholson G
Department of Statistics, University of Oxford, 1 South Parks Road, Oxford OX1 3TG, UK.
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Nyholt DR
QIMR Berghofer Medical Research Institute, Brisbane, Queensland 4006, Australia.
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Olsson C
Cardiothoracic Surgery Unit, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm 17176, Sweden.
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Perry JR
Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.
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Reinmaa E
Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.
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Salem RM
Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA 02115, USA.
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Sandholm N
Department of Biomedical Engineering and Computational Science, Aalto University School of Science, Helsinki, Finland.
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Schadt EE
Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10580, USA.
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Scott RA
MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK.
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Stolk L
Netherlands Consortium for Healthy Aging (NCHA), Leiden University Medical Center, Leiden 2300 RC, The Netherlands.
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Vallejo EE
Computer Science Department, Tecnológico de Monterrey, Atizapán de Zaragoza, 52926, Mexico.
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Westra HJ
Department of Genetics, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.
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Zondervan KT
Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.
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Amouyel P
Center for Human Genetics Research, Vanderbilt University Medical Center, Nashville TN 37203, USA.
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Arveiler D
Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
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Bakker SJ
Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden, Stockholm 17177, Sweden.
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Beilby J
Biological Psychology, VU University Amsterdam, 1081BT Amsterdam, The Netherlands.
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Bergman RN
Department of Internal Medicine B, University Medicine Greifswald, D-17475 Greifswald, Germany.
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Blangero J
Clinic of Cardiology, West-German Heart Centre, University Hospital Essen, Essen, Germany.
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Brown MJ
National Institute for Health and Welfare, FI-00271 Helsinki, Finland.
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Burnier M
Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.
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Campbell H
Department of Internal Medicine, University of Pisa, Pisa, Italy.
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Chakravarti A
Department of Cardiology, Toulouse University School of Medicine, Rangueil Hospital, Toulouse, France.
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Chines PS
MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK.
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Claudi-Boehm S
UWI Solutions for Developing Countries, The University of the West Indies, Mona, Kingston 7, Jamaica.
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Collins FS
Netherlands Consortium for Healthy Aging (NCHA), 3015GE Rotterdam, The Netherlands.
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Crawford DC
Department of Internal Medicine, University Medical Center Groningen, University of Groningen, 9700RB Groningen, The Netherlands.
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Danesh J
Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.
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de Faire U
Icelandic Heart Association, Kopavogur 201, Iceland.
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de Geus EJ
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
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Dörr M
Laboratory of Epidemiology and Population Sciences, National Institute on Aging, NIH, Bethesda, MD 20892, USA.
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Erbel R
Institute of Biomedical & Clinical Science, University of Exeter, Barrack Road, Exeter EX2 5DW, UK.
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Eriksson JG
National Institute for Health and Welfare, FI-00271 Helsinki, Finland.
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Farrall M
Center for Biomedicine, European Academy Bozen, Bolzano (EURAC), Bolzano 39100, Italy - Affiliated Institute of the University of Lübeck, D-23562 Lübeck, Germany.
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Ferrannini E
Institute of Cardiovascular Science, University College London, London WC1E 6BT, UK.
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Ferrières J
Institute for Community Medicine, University Medicine Greifswald, D-17475 Greifswald, Germany.
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Forouhi NG
Netherlands Consortium for Healthy Aging (NCHA), 3015GE Rotterdam, The Netherlands.
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Forrester T
Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, D-17475 Greifswald, Germany.
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Franco OH
Centre for Cardiovascular Genetics, Institute Cardiovascular Sciences, University College London, London WC1E 6JJ, UK.
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Gansevoort RT
Sansom Institute for Health Research, University of South Australia, Adelaide 5000, South Australia, Australia.
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Gieger C
Research Unit of Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.
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Gudnason V
Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK.
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Haiman CA
Department of Biology, Norwegian University of Science and Technology, Trondheim, Norway.
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Harris TB
National Institute for Health and Welfare, FI-00271 Helsinki, Finland.
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Hattersley AT
National Institute for Health and Welfare, FI-00271 Helsinki, Finland.
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Heliövaara M
National Institute for Health and Welfare, FI-00271 Helsinki, Finland.
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Hicks AA
UK Clinical Research Collaboration Centre of Excellence for Public Health (NI), Queens University of Belfast, Belfast, Northern Ireland.
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Hingorani AD
Institute of Health Sciences, Faculty of Medicine, University of Oulu, Oulu, Finland.
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Hoffmann W
Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK.
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Hofman A
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
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Homuth G
Integrated Research and Treatment Center (IFB) Adiposity Diseases, University of Leipzig, D-04103 Leipzig, Germany.
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Humphries SE
Department of Genetics, Washington University School of Medicine, St. Louis, MO 63110, USA.
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Hyppönen E
Department of Epidemiology and Public Health, University College London, London WC1E 6BT, UK.
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Illig T
National Institute for Health and Welfare, FI-00271 Helsinki, Finland.
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Jarvelin MR
Department of Medicine, Kuopio University Hospital and University of Eastern Finland, FI-70210 Kuopio, Finland.
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Johansen B
Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.
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Jousilahti P
MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK.
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Jula AM
Epidemiology Program, University of Hawaii Cancer Center, Honolulu, HI USA.
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Kaprio J
Department of Clinical Chemistry, Fimlab Laboratories and School of Medicine University of Tampere, FI-33520 Tampere, Finland.
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Kee F
Steno Diabetes Center A/S, Gentofte DK-2820, Denmark.
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Keinanen-Kiukaanniemi SM
National Institute for Health and Welfare, FI-00271 Helsinki, Finland.
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Kooner JS
Institut Universitaire de Cardiologie et de Pneumologie de Québec, Faculty of Medicine, Laval University, Quebec, QC G1V 0A6, Canada.
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Kooperberg C
Department of Genetics, Rutgers University, Piscataway, NJ USA.
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Kovacs P
UWI Solutions for Developing Countries, The University of the West Indies, Mona, Kingston 7, Jamaica.
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Kraja AT
Department of Biostatistics, University of Washington, Seattle, WA 98195, USA.
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Kumari M
Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia 6009, Australia.
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Kuulasmaa K
Clinic of Cardiology, West-German Heart Centre, University Hospital Essen, Essen, Germany.
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Kuusisto J
Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK.
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Lakka TA
Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.
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Langenberg C
Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg 413 45, Sweden.
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Le Marchand L
Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
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Lehtimäki T
MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK.
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Lyssenko V
Epidemiology and Obstetrics & Gynaecology, University of Toronto, Toronto, Ontario, Canada.
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Männistö S
Institute for Research in Extramural Medicine, Institute for Health and Care Research, VU University, 1081BT Amsterdam, The Netherlands.
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Marette A
Research Unit of Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.
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Matise TC
Center for Biomedicine, European Academy Bozen, Bolzano (EURAC), Bolzano 39100, Italy - Affiliated Institute of the University of Lübeck, D-23562 Lübeck, Germany.
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McKenzie CA
Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, FI-20521 Turku, Finland.
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McKnight B
Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA.
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Musk AW
Department of Genetics, Washington University School of Medicine, St. Louis, MO 63110, USA.
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Möhlenkamp S
Division of Biostatistics, Washington University School of Medicine, St. Louis, MO 63110, USA.
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Morris AD
Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA 02215, USA.
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Nelis M
Center for Systems Genomics, The Pennsylvania State University, University Park, PA 16802, USA.
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Ohlsson C
Center for Human Genetics Research, Vanderbilt University Medical Center, Nashville TN 37203, USA.
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Oldehinkel AJ
National Institute for Health and Welfare, FI-00271 Helsinki, Finland.
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Ong KK
Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Leicester LE3 9QP, UK.
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Palmer LJ
South Carelia Central Hospital, 53130 Lappeenranta, Finland.
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Penninx BW
Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA.
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Peters A
Department of Medicine III, University Hospital Carl Gustav Carus, Technische Universität Dresden, D-01307 Dresden, Germany.
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Pramstaller PP
Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
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Raitakari OT
Department of Epidemiology, Maastricht University, Maastricht, The Netherlands.
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Rankinen T
deCODE Genetics, Amgen inc., Reykjavik 101, Iceland.
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Rao DC
Department of Epidemiology, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.
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Rice TK
Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.
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Ridker PM
Integrated Research and Treatment Center (IFB) Adiposity Diseases, University of Leipzig, D-04103 Leipzig, Germany.
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Ritchie MD
Department of Kinesiology, Laval University, Quebec, QC G1V 0A6, Canada.
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Rudan I
Dipartimento di Scienze Farmacologiche e Biomolecolari, Università di Milano & Centro Cardiologico Monzino, Instituto di Ricovero e Cura a Carattere Scientifico, Milan 20133, italy.
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Salomaa V
Institute of Nutrition and Functional Foods, Laval University, Quebec, QC G1V 0A6, Canada.
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Samani NJ
Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, D-17475 Greifswald, Germany.
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Saramies J
Department of Internal Medicine, University Hospital (CHUV) and University of Lausanne, 1011, Switzerland.
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Sarzynski MA
Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, Scotland, UK.
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Schwarz PE
Department of Epidemiology, Erasmus MC University Medical Center, 3015GE Rotterdam, The Netherlands.
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Shuldiner AR
Department of Nutrition, University of North Carolina, Chapel Hill, NC 27599, USA.
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Staessen JA
Institute of Social and Preventive Medicine (IUMSP), Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland.
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Steinthorsdottir V
Lee Kong Chian School of Medicine, Imperial College London and Nanyang Technological University, Singapore, 637553 Singapore, Singapore.
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Stolk RP
Department of Medicine III, University Hospital Carl Gustav Carus, Technische Universität Dresden, D-01307 Dresden, Germany.
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Strauch K
Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA.
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Tönjes A
CNRS UMR 8199, F-59019 Lille, France.
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Tremblay A
Clinical Pharmacology and Barts and The London Genome Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK.
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Tremoli E
Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK.
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Vohl MC
Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA 02215, USA.
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Völker U
Department of Public Health Sciences, Stritch School of Medicine, Loyola University of Chicago, Maywood, IL 61053, USA.
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Vollenweider P
Department of Dietetics-Nutrition, Harokopio University, Athens, Greece.
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Wilson JF
Translational Gerontology Branch, National Institute on Aging, Baltimore MD 21225, USA.
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Witteman JC
Department of Genomics of Common Disease, School of Public Health, Imperial College London, Hammersmith Hospital, London, UK.
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Adair LS
Department of Psychiatry and Psychotherapy, University Medicine Greifswald, HELIOS-Hospital Stralsund, D-17475 Greifswald, Germany.
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Bochud M
Atherosclerosis Research Unit, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm 17176, Sweden.
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Boehm BO
PathWest Laboratory Medicine of Western Australia, NEDLANDS, Western Australia 6009, Australia.
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Bornstein SR
Department of Public Health and General Practice, Norwegian University of Science and Technology, Trondheim 7489, Norway.
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Bouchard C
Institute for Medical Informatics, Biometry and Epidemiology (IMIBE), University Hospital Essen, Essen, Germany.
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Cauchi S
Department of Epidemiology and Public Health, University College London, London WC1E 6BT, UK.
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Caulfield MJ
MRC Unit for Lifelong Health and Ageing at University College London, London WC1B 5JU, UK.
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Chambers JC
Department of Medicine, Kuopio University Hospital and University of Eastern Finland, FI-70210 Kuopio, Finland.
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Chasman DI
Center for Human Genetics, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA.
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Cooper RS
Vth Department of Medicine (Nephrology, Hypertensiology, Endocrinology, Diabetology, Rheumatology), Medical Faculty of Mannheim, University of Heidelberg, Germany.
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Dedoussis G
Clinical Pharmacology and Barts and The London Genome Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK.
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Ferrucci L
Department of Community Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø, Norway.
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Froguel P
Genetic Epidemiology Unit, Department of Epidemiology, Erasmus MC University Medical Center, 3015 GE Rotterdam, The Netherlands.
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Grabe HJ
Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK.
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Hamsten A
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm 17177, Sweden.
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Hui J
Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.
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Hveem K
Institute of Nutrition and Functional Foods, Laval University, Quebec, QC G1V 0A6, Canada.
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Jöckel KH
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
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Kivimaki M
Population, Policy, and Practice, University College London Institute of Child Health, London WC1N 1EH, UK.
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Kuh D
Department of Medicine, Stanford University School of Medicine, Palo Alto, CA, USA.
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Laakso M
Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.
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Liu Y
Netherlands Consortium for Healthy Aging (NCHA), 3015GE Rotterdam, The Netherlands.
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März W
Finnish Diabetes Association, Kirjoniementie 15, FI-33680 Tampere, Finland.
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Munroe PB
Biological Psychology, VU University Amsterdam, 1081BT Amsterdam, The Netherlands.
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Njølstad I
Helsinki University Central Hospital Heart and Lung Center, Department of Medicine, Helsinki University Central Hospital, FI-00290 Helsinki, Finland.
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Oostra BA
Netherlands Consortium for Healthy Aging (NCHA), Leiden University Medical Center, Leiden 2300 RC, The Netherlands.
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Palmer CN
Department of Epidemiology, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.
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Pedersen NL
Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK.
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Perola M
deCODE Genetics, Amgen inc., Reykjavik 101, Iceland.
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Pérusse L
Integrated Research and Treatment Center (IFB) Adiposity Diseases, University of Leipzig, D-04103 Leipzig, Germany.
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Peters U
National Institute for Health and Welfare, FI-00271 Helsinki, Finland.
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Power C
Netherlands Consortium for Healthy Aging (NCHA), 3015GE Rotterdam, The Netherlands.
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Quertermous T
Department of Public Health and Clinical Nutrition, University of Eastern Finland, Finland.
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Rauramaa R
Department of Genetics, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.
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Rivadeneira F
EPIMED Research Center, Department of Clinical and Experimental Medicine, University of Insubria, Varese, Italy.
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Saaristo TE
Institute of Cellular Medicine, Newcastle University, Newcastle NE1 7RU, UK.
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Saleheen D
MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK.
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Sinisalo J
Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.
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Slagboom PE
Institute of Medical Informatics, Biometry and Epidemiology, Chair of Epidemiology, Ludwig-Maximilians-Universität, D-85764 Munich, Germany.
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Snieder H
Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA.
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Spector TD
Department of Medicine, Stanford University School of Medicine, Palo Alto, CA, USA.
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Stefansson K
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
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Stumvoll M
Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA.
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Tuomilehto J
Department of Genetics, Washington University School of Medicine, St. Louis, MO 63110, USA.
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Uitterlinden AG
Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.
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Uusitupa M
Department of Genetics, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.
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van der Harst P
Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter EX1 2LU, UK.
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Veronesi G
Institute for Molecular Medicine, University of Helsinki, FI-00014 Helsinki, Finland.
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Walker M
Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.
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Wareham NJ
Albert Einstein College of Medicine. Department of Epidemiology and Population Health, Belfer 1306, NY 10461, USA.
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Watkins H
Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
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Wichmann HE
Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.
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Abecasis GR
Laboratory of Genetics, National Institute on Aging, Baltimore, MD 21224, USA.
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Assimes TL
Division of Population Health Sciences & Education, St George's, University of London, London SW17 0RE, UK.
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Berndt SI
deCODE Genetics, Amgen inc., Reykjavik 101, Iceland.
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Boehnke M
Genetic Epidemiology Unit, Department of Epidemiology, Erasmus MC University Medical Center, 3015 GE Rotterdam, The Netherlands.
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Borecki IB
Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI, USA.
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Deloukas P
Queensland Brain Institute, The University of Queensland, Brisbane 4072, Australia.
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Franke L
Queensland Brain Institute, The University of Queensland, Brisbane 4072, Australia.
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Frayling TM
Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA 02115, USA.
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Groop LC
Netherlands Consortium for Healthy Aging (NCHA), 3015GE Rotterdam, The Netherlands.
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Hunter DJ
Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.
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Kaplan RC
Department of Internal Medicine, Division of Gastroenterology, and Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109.
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O'Connell JR
Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
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Qi L
National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham MA 01702, USA.
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Schlessinger D
Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.
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Strachan DP
Department of Public Health and Clinical Medicine, Unit of Medicine, Umeå University, Umeå 901 87, Sweden.
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Thorsteinsdottir U
Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.
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van Duijn CM
Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, D-93053 Regensburg, Germany.
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Willer CJ
MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK.
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Visscher PM
Department of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA.
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Yang J
Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.
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Hirschhorn JN
Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.
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Zillikens MC
Department of Genetics, University of North Carolina, Chapel Hill, NC 27599, USA.
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McCarthy MI
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Speliotes EK
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North KE
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Fox CS
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Barroso I
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Franks PW
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Ingelsson E
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Heid IM
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Loos RJ
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Cupples LA
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Morris AP
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Lindgren CM
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Mohlke KL
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English
Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic outcomes, independent of overall adiposity. To increase our understanding of the genetic basis of body fat distribution and its molecular links to cardiometabolic traits, here we conduct genome-wide association meta-analyses of traits related to waist and hip circumferences in up to 224,459 individuals. We identify 49 loci (33 new) associated with waist-to-hip ratio adjusted for body mass index (BMI), and an additional 19 loci newly associated with related waist and hip circumference measures (P < 5 × 10(-8)). In total, 20 of the 49 waist-to-hip ratio adjusted for BMI loci show significant sexual dimorphism, 19 of which display a stronger effect in women. The identified loci were enriched for genes expressed in adipose tissue and for putative regulatory elements in adipocytes. Pathway analyses implicated adipogenesis, angiogenesis, transcriptional regulation and insulin resistance as processes affecting fat distribution, providing insight into potential pathophysiological mechanisms.
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green
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https://sonar.ch/global/documents/242706
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