Borna Disease in a Dog with Lethal Meningoencephalitis
- Weissenböck, Herbert Institute of Pathology and Forensic Veterinary Medicine 1 and
- Nowotny, Norbert Institute of Virology, 2 University of Veterinary Medicine, A-1210 Vienna, Austria, and
- Caplazi, Patrick Institute of Veterinary Pathology, University of Zurich, CH-8057 Zurich, Switzerland 3
- Kolodziejek, Jolanta Institute of Virology, 2 University of Veterinary Medicine, A-1210 Vienna, Austria, and
- Ehrensperger, Felix Institute of Veterinary Pathology, University of Zurich, CH-8057 Zurich, Switzerland 3
Published in:
- Journal of Clinical Microbiology. - American Society for Microbiology. - 1998, vol. 36, no. 7, p. 2127-2130
English
A dog was euthanatized because of progressive neurological signs. Histologically, a nonsuppurative meningoencephalitis was found. By immunohistochemistry, in situ hybridization, and nested PCR procedures, Borna disease virus (BDV) antigen and BDV-specific RNA were demonstrated in brain tissues of the dog. The nucleotide sequence of the PCR product showed 94 to 98% homology to published BDV sequences. This is the first description of Borna disease in a dog.
- Language
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- English
- Open access status
- bronze
- Identifiers
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- DOI 10.1128/jcm.36.7.2127-2130.1998
- ISSN 1098-660X
- Persistent URL
- https://sonar.ch/global/documents/244709
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