Journal article

Physiology of iron metabolism.

  • Waldvogel-Abramowski S Service régional vaudois de transfusion sanguine, Epalinges, Switzerland.
  • Waeber G Service de médecine interne, CHUV, Lausanne, Switzerland.
  • Gassner C Blutspende Zurich, Schlieren, Switzerland.
  • Buser A Blutspende Beiderbasel, Basel, Switzerland.
  • Frey BM Blutspende Zurich, Schlieren, Switzerland.
  • Favrat B Department of Ambulatory Care and Community Medicine, Lausanne, Switzerland.
  • Tissot JD Service régional vaudois de transfusion sanguine, Epalinges, Switzerland.
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  • 2014-07-24
Published in:
  • Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie. - 2014
English A revolution occurred during the last decade in the comprehension of the physiology as well as in the physiopathology of iron metabolism. The purpose of this review is to summarize the recent knowledge that has accumulated, allowing a better comprehension of the mechanisms implicated in iron homeostasis. Iron metabolism is very fine tuned. The free molecule is very toxic; therefore, complex regulatory mechanisms have been developed in mammalian to insure adequate intestinal absorption, transportation, utilization, and elimination. 'Ironomics' certainly will be the future of the understanding of genes as well as of the protein-protein interactions involved in iron metabolism.
Language
  • English
Open access status
bronze
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Persistent URL
https://sonar.ch/global/documents/24512
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