Total ankle replacement in patients with von Willebrand disease: mid-term results of 18 procedures.
Journal article

Total ankle replacement in patients with von Willebrand disease: mid-term results of 18 procedures.

  • Barg K Orthopaedic Department, University Hospital of Basel, Basel, Switzerland.
  • Wiewiorski M Orthopaedic Department, University Hospital of Basel, Basel, Switzerland.
  • Anderson AE Department of Orthopaedics, Harold K. Dunn Orthopaedic Research Laboratory, University of Utah, Salt Lake City, UT, USA.
  • Schneider SW Department of Dermatology Venerology and Allergology, University Medical Center and Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.
  • Wimmer MD Department of Orthopaedics and Trauma Surgery, University of Bonn, Bonn, Germany.
  • Wirtz DC Department of Orthopaedics and Trauma Surgery, University of Bonn, Bonn, Germany.
  • Valderrabano V Orthopaedic Department, University Hospital of Basel, Basel, Switzerland.
  • Barg A Orthopaedic Department, University Hospital of Basel, Basel, Switzerland.
  • Pagenstert G Orthopaedic Department, University Hospital of Basel, Basel, Switzerland.
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  • 2015-02-18
Published in:
  • Haemophilia : the official journal of the World Federation of Hemophilia. - 2015
English von Willebrand disease (VWD) is a recognized cause of secondary ankle osteoarthritis (OA). Few studies have examined orthopaedic complications and outcomes in VWD patients treated for end-stage ankle OA with total ankle replacement (TAR). To determine the clinical presentation, intraoperative and postoperative complications and evaluate the mid-term outcome in VWD patients treated with TAR. Eighteen patients with VWD with mean age 47.3 years (range = 34.0-68.7) were treated for end-stage ankle OA with TAR. The mean duration of follow-up was 7.5 years (range = 2.9-13.2). Intraoperative and perioperative complications were recorded. Component stability was assessed with weight-bearing radiographs. Clinical evaluation included range of motion (ROM) tests using a goniometer and under fluoroscopy using a lateral view. Clinical outcomes were analysed by a visual analogue scale, the American Orthopaedic Foot and Ankle Society hindfoot score and Short Form (36) Health Survey (SF-36) health survey. One patient sustained an intraoperative medial malleolar fracture. In two patients delayed wound healing was observed. Two secondary major surgeries were performed. Pain level decreased from 8.2 ± 0.9 (range = 7-10) preoperatively to 1.1 ± 1.2 (range = 0-4) postoperatively. Significant functional improvement including ROM was observed. All categories of SF-36 score showed significant improvement in quality of life. Mid-term results of TAR in patients with VWD are encouraging. The total rate of intraoperative and postoperative complications was 33.3%. However, longer term outcomes are necessary to fully understand the clinical benefit of TAR in patients with VWD.
Language
  • English
Open access status
closed
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Persistent URL
https://sonar.ch/global/documents/247590
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