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Progress in Conductive Polyaniline-Based Nanocomposites for Biomedical Applications: A Review.
Journal article

Progress in Conductive Polyaniline-Based Nanocomposites for Biomedical Applications: A Review.

  • Zare EN School of Chemistry , Damghan University , Damghan 36716-41167 , Iran.
  • Makvandi P Department of Medical Nanotechnology, Faculty of Advanced Technology in Medicine , Iran University of Medical Sciences , Tehran 14496-14535 , Iran.
  • Ashtari B Department of Medical Nanotechnology, Faculty of Advanced Technology in Medicine , Iran University of Medical Sciences , Tehran 14496-14535 , Iran.
  • Rossi F Department of Chemistry, Materials and Chemical Engineering , Politecnico di Milano Technical University , Milano 20133 , Italy.
  • Motahari A Young Researchers and Elite Club, Jahrom Branch , Islamic Azad University , Jahrom 74147-85318 , Iran.
  • Perale G Biomaterials Laboratory, Institute for Mechanical Engineering and Materials Technology , University of Applied Sciences and Arts of Southern Switzerland , Manno 6928 , Switzerland.
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  • 2019-09-11
Published in:
  • Journal of medicinal chemistry. - 2020
Aniline Compounds
Animals
Anti-Bacterial Agents
Antioxidants
Biocompatible Materials
Biodegradable Plastics
Biosensing Techniques
Cell Line, Tumor
Drug Carriers
Electric Conductivity
Humans
Nanocomposites
Tissue Engineering
English Inherently conducting polymers (ICPs) are a specific category of synthetic polymers with distinctive electro-optic properties, which involve conjugated chains with alternating single and double bonds. Polyaniline (PANI), as one of the most well-known ICPs, has outstanding potential applications in biomedicine because of its high electrical conductivity and biocompatibility caused by its hydrophilic nature, low-toxicity, good environmental stability, and nanostructured morphology. Some of the limitations in the use of PANI, such as its low processability and degradability, can be overcome by the preparation of its blends and nanocomposites with various (bio)polymers and nanomaterials, respectively. This review describes the state-of-the-art of biological activities and applications of conductive PANI-based nanocomposites in the biomedical fields, such as antimicrobial therapy, drug delivery, biosensors, nerve regeneration, and tissue engineering. The latest progresses in the biomedical applications of PANI-based nanocomposites are reviewed to provide a background for future research.
Language
  • English
Open access status
closed
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Persistent URL
https://sonar.ch/global/documents/249290
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