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Contemporary registries on P2Y12 inhibitors in patients with acute coronary syndromes in Europe: overview and methodological considerations.

  • Jukema JW Department of Cardiology, Leiden University Medical Center, Albinusdreef 2, ZA 2333 Leiden, The Netherlands j.w.jukema@lumc.nl.
  • Lettino M Cardiology Unit, Humanitas Research Hospital, Rozzano (Milano), Italy.
  • Widimský P Cardiocenter, Third Faculty of Medicine, Charles University, Prague, Czech Republic.
  • Danchin N Department of Cardiology, Hôpital Européen Georges-Pompidou, Paris, France.
  • Bardaji A Cardiology Service, Hospital Universitari de Tarragona Joan XXIII, IISPV Tarragona, Tarragona, Spain.
  • Barrabes JA Cardiology Service, Hospital Universitari Vall d'Hebron, Barcelona, Spain.
  • Cequier A Heart Disease Institute, Bellvitge University Hospital IDIBELL, University of Barcelona, Barcelona, Spain.
  • Claeys MJ Department of Cardiology, University Hospital Antwerp, Edegem, Belgium.
  • De Luca L Department of Cardiovascular Sciences, Laboratory of Interventional Cardiology, European Hospital, Rome, Italy.
  • Dörler J University Clinic of Internal Medicine III, Cardiology and Angiology, Medical University of Innsbruck, Innsbruck, Austria.
  • Erlinge D Department of Cardiology, Skåne University Hospital Lund, Lund, Sweden.
  • Erne P AMIS-Plus Data Center, University of Zurich, Zurich, Switzerland.
  • Goldstein P Pôle de l 'urgence, Service de SAMU du Nord, Centre Hospitalier régional Universitaire de Lille, Lille, France.
  • Koul SM Department of Cardiology, Skåne University Hospital Lund, Lund, Sweden.
  • Lemesle G Cardiac Intensive Care Unit, Interventional Cardiology Hopital Cardiologique, Centre Hospitalier Régional et Universitaire de Lille, Lille, France.
  • Lüscher TF Cardiology Department, Center for Molecular Cardiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
  • Matter CM Cardiology Department, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
  • Montalescot G Cardiac Care Unit, Institute of Cardiology, Pitié-Salpêtrière University Hospital, Paris, France.
  • Radovanovic D Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland.
  • Lopez-Sendón J Cardiology Department, Hospital Universitario La Paz, IdiPaz, Madrid, Spain.
  • Tousek P Cardiocenter, Third Faculty of Medicine, Charles University, Prague, Czech Republic.
  • Weidinger F 2nd Department of Medicine with Cardiology and Intensive Care, Hospital Rudolfstiftung, Vienna, Austria.
  • Weston CF Swansea University, College of Medicine, Swansea, Wales, UK.
  • Zaman A Department of Cardiology, Freeman Hospital, and Institute of Cellular Medicine, Faculty of Medical Sciences, Newcastle University, Newcastle-upon-Tyne, UK.
  • Zeymer U Interventional Cardiology, Institut für Herzinfarktforschung Ludwigshafen, Ludwigshafen am Rhein, Germany.
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  • 2016-08-18
Published in:
  • European heart journal. Cardiovascular pharmacotherapy. - 2015
Acute coronary syndrome
Antithrombotics
Clopidogrel
Methodology
Non-ST-segment myocardial infarction
Observational
P2Y12 inhibitors
Prasugrel
Real-world evidence
Registries
ST-segment elevation myocardial infarction
Ticagrelor
Acute Coronary Syndrome
Europe
Humans
Purinergic P2Y Receptor Antagonists
Registries
English Patient registries that document real-world clinical experience play an important role in cardiology as they complement the data from randomized controlled trials, provide valuable information on drug use and clinical outcomes, and evaluate to what extent guidelines are followed in practice. The Platelet Inhibition Registry in ACS EvalUation Study (PIRAEUS) project is an initiative of registry holders who are managing national or international registries observing patients with acute coronary syndromes (ACS). The aim of PIRAEUS is to systematically compare and combine available information/insights from various European ACS registries with a focus on P2Y12 inhibitors. The present publication introduces the 17 participating registries in a narrative and tabular form, and describes which ACS groups and which dual antiplatelet therapies were investigated. It sets the basis for upcoming publications that will focus on effectiveness and safety of the antiplatelets used.
Language
  • English
Open access status
bronze
Identifiers
Persistent URL
https://sonar.ch/global/documents/252400
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