Adaptive Statistical Iterative Reconstruction-V: Impact on Image Quality in Ultralow-Dose Coronary Computed Tomography Angiography.
- Benz DC From the Department of Nuclear Medicine, Cardiac Imaging, University Hospital Zurich, Ramistrasse, Zurich, Switzerland.
- Gräni C
- Mikulicic F
- Vontobel J
- Fuchs TA
- Possner M
- Clerc OF
- Stehli J
- Gaemperli O
- Pazhenkottil AP
- Buechel RR
- Kaufmann PA
- 2016-08-26
Published in:
- Journal of computer assisted tomography. - 2016
Algorithms
Computed Tomography Angiography
Coronary Angiography
Coronary Artery Disease
Data Interpretation, Statistical
Female
Humans
Male
Middle Aged
Observer Variation
Radiation Exposure
Radiation Protection
Radiographic Image Enhancement
Radiographic Image Interpretation, Computer-Assisted
Reproducibility of Results
Sensitivity and Specificity
English
OBJECTIVE
The clinical utility of a latest generation iterative reconstruction algorithm (adaptive statistical iterative reconstruction [ASiR-V]) has yet to be elucidated for coronary computed tomography angiography (CCTA). This study evaluates the impact of ASiR-V on signal, noise and image quality in CCTA.
METHODS
Sixty-five patients underwent clinically indicated CCTA on a 256-slice CT scanner using an ultralow-dose protocol. Data sets from each patient were reconstructed at 6 different levels of ASiR-V. Signal intensity was measured by placing a region of interest in the aortic root, LMA, and RCA. Similarly, noise was measured in the aortic root. Image quality was visually assessed by 2 readers.
RESULTS
Median radiation dose was 0.49 mSv. Image noise decreased with increasing levels of ASiR-V resulting in a significant increase in signal-to-noise ratio in the RCA and LMA (P < 0.001). Correspondingly, image quality significantly increased with higher levels of ASiR-V (P < 0.001).
CONCLUSIONS
ASiR-V yields substantial noise reduction and improved image quality enabling introduction of ultralow-dose CCTA.
The clinical utility of a latest generation iterative reconstruction algorithm (adaptive statistical iterative reconstruction [ASiR-V]) has yet to be elucidated for coronary computed tomography angiography (CCTA). This study evaluates the impact of ASiR-V on signal, noise and image quality in CCTA.
METHODS
Sixty-five patients underwent clinically indicated CCTA on a 256-slice CT scanner using an ultralow-dose protocol. Data sets from each patient were reconstructed at 6 different levels of ASiR-V. Signal intensity was measured by placing a region of interest in the aortic root, LMA, and RCA. Similarly, noise was measured in the aortic root. Image quality was visually assessed by 2 readers.
RESULTS
Median radiation dose was 0.49 mSv. Image noise decreased with increasing levels of ASiR-V resulting in a significant increase in signal-to-noise ratio in the RCA and LMA (P < 0.001). Correspondingly, image quality significantly increased with higher levels of ASiR-V (P < 0.001).
CONCLUSIONS
ASiR-V yields substantial noise reduction and improved image quality enabling introduction of ultralow-dose CCTA.
- Language
-
- English
- Open access status
- green
- Identifiers
-
- DOI 10.1097/RCT.0000000000000460
- PMID 27560012
- Persistent URL
- https://sonar.ch/global/documents/252402
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