Plant development regulated by cytokinin sinks.
- Zürcher E Zürich-Basel Plant Science Center, Department of Plant and Microbial Biology, University of Zürich, 8008 Zürich, Switzerland.
- Liu J Zürich-Basel Plant Science Center, Department of Plant and Microbial Biology, University of Zürich, 8008 Zürich, Switzerland.
- di Donato M Plant Biology, Department of Biology, University of Fribourg, 1700 Fribourg, Switzerland.
- Geisler M Plant Biology, Department of Biology, University of Fribourg, 1700 Fribourg, Switzerland.
- Müller B Zürich-Basel Plant Science Center, Department of Plant and Microbial Biology, University of Zürich, 8008 Zürich, Switzerland. bruno.mueller@uzh.ch.
- 2016-10-05
Published in:
- Science (New York, N.Y.). - 2016
Arabidopsis
Arabidopsis Proteins
Cell Membrane
Cytokinins
Ligands
Meristem
Nucleobase Transport Proteins
Plant Roots
Plant Shoots
Signal Transduction
English
Morphogenetic signals control the patterning of multicellular organisms. Cytokinins are mobile signals that are perceived by subsets of plant cells. We found that the responses to cytokinin signaling during Arabidopsis development are constrained by the transporter PURINE PERMEASE 14 (PUP14). In our experiments, the expression of PUP14 was inversely correlated to the cytokinin signaling readout. Loss of PUP14 function allowed ectopic cytokinin signaling accompanied by aberrant morphogenesis in embryos, roots, and the shoot apical meristem. PUP14 protein localized to the plasma membrane and imported bioactive cytokinins, thus depleting apoplastic cytokinin pools and inhibiting perception by plasma membrane-localized cytokinin sensors to create a sink for active ligands. We propose that the spatiotemporal cytokinin sink patterns established by PUP14 determine the cytokinin signaling landscape that shapes the morphogenesis of land plants.
- Language
-
- English
- Open access status
- green
- Identifiers
-
- DOI 10.1126/science.aaf7254
- PMID 27701112
- Persistent URL
- https://sonar.ch/global/documents/252435
Statistics
Document views: 29
File downloads:
- Full-text: 0