[Can cannabis use increase the risk for schizophrenic psychoses?].
- Bugra H Zentrum für Gender Research und Früherkennung, Universitäre Psychiatrische Kliniken, Universitätsspital Basel, Schweiz.
- Rapp C
- Studerus E
- Aston J
- Borgwardt S
- Riecher-Rössler A
- 2012-11-10
Published in:
- Fortschritte der Neurologie-Psychiatrie. - 2012
Adolescent
Adult
Age of Onset
Cognition Disorders
Genetic Predisposition to Disease
Humans
Marijuana Smoking
Middle Aged
Motivation
Psychoses, Substance-Induced
Risk
Schizophrenia
Schizophrenic Psychology
Young Adult
English
BACKGROUND
In recent years, cannabis has been increasingly discussed as one of the most important environmental risk factors for developing schizophrenic psychoses. This is mainly due to the following observations. (i) Cannabis at high doses can cause acute transient psychotic symptoms even in healthy individuals. (ii) Patients with schizophrenia abuse cannabis more often than age-matched healthy controls.
OBJECTIVES
It is still controversial whether cannabis use can cause schizophrenic psychoses that would not have occurred otherwise. In our review, we have critically evaluated the evidence for a causal link between cannabis use and schizophrenic psychoses.
METHODS
A systematic literature review in PubMed, ISI Web of Science and PsycINFO was carried out using the following keywords: cannabis, marijuana, THC, hashish, psychosis, schizophrenia.
CONCLUSIONS
We have concluded that although a causal relationship between cannabis use and schizophrenic psychoses cannot be definitely proven, the available evidence strongly supports its plausibility. Furthermore, the results of the review indicate that cannabis might cause psychosis especially in individuals with a predisposition for schizophrenia and in adolescents with an early onset of cannabis use.
In recent years, cannabis has been increasingly discussed as one of the most important environmental risk factors for developing schizophrenic psychoses. This is mainly due to the following observations. (i) Cannabis at high doses can cause acute transient psychotic symptoms even in healthy individuals. (ii) Patients with schizophrenia abuse cannabis more often than age-matched healthy controls.
OBJECTIVES
It is still controversial whether cannabis use can cause schizophrenic psychoses that would not have occurred otherwise. In our review, we have critically evaluated the evidence for a causal link between cannabis use and schizophrenic psychoses.
METHODS
A systematic literature review in PubMed, ISI Web of Science and PsycINFO was carried out using the following keywords: cannabis, marijuana, THC, hashish, psychosis, schizophrenia.
CONCLUSIONS
We have concluded that although a causal relationship between cannabis use and schizophrenic psychoses cannot be definitely proven, the available evidence strongly supports its plausibility. Furthermore, the results of the review indicate that cannabis might cause psychosis especially in individuals with a predisposition for schizophrenia and in adolescents with an early onset of cannabis use.
- Language
-
- English
- Open access status
- green
- Identifiers
-
- DOI 10.1055/s-0032-1325415
- PMID 23139065
- Persistent URL
- https://sonar.ch/global/documents/252741
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