Effect of sodium, amine and stannous fluoride at the same concentration and different pH on in vitro erosion.
- Wiegand A Clinic for Preventive Dentistry, Periodontology and Cariology, University of Zürich, Plattenstrasse 11, CH-8032 Zürich, Switzerland. annette.wiegand@zzmk.unizh.ch
- Bichsel D
- Magalhães AC
- Becker K
- Attin T
- 2009-05-01
Published in:
- Journal of dentistry. - 2009
Administration, Topical
Animals
Cattle
Dental Enamel
Dental Pellicle
Dose-Response Relationship, Drug
Fluorides, Topical
Humans
Hydrogen-Ion Concentration
Sodium Fluoride
Tin Fluorides
Tooth Demineralization
Tooth Erosion
Tooth Remineralization
English
OBJECTIVE
This study aimed to compare the effects 0.5% and 1% sodium, amine and stannous fluoride at different pH on enamel erosion in vitro.
METHODS
Bovine enamel samples were submitted to a cyclic de- and remineralisation for 3 days. Each day, the samples were exposed for 120 min to pooled human saliva and subsequently treated with one of the fluoride solutions for 3 min: amine fluoride (AmF, 0.5% and 1% F(-)), sodium fluoride (NaF, 0.5% and 1% F(-)), each at pH 3.9 and 7.0, and stannous fluoride (SnF(2), 0.5% and 1% F(-)), at pH: 3.9. Additionally, two groups were treated with fluoride-free placebo solutions (pH: 3.9 and 7.0) and one group served as control (no fluoridation). Ten specimens each group were inserted in a so-called artificial mouth and eroded six times daily with hydrochloric acid (pH 2.6) for 90 s each intermitted by exposure to artificial saliva (1h). After 3 days, enamel loss was analyzed profilometrically and evaluated statistically by ANOVA.
RESULTS
Only the acidic 0.5% and 1% SnF(2) and 1% AmF solutions were able to reduce erosive enamel loss significantly, while all other solutions and placebos did not differ significantly from the control. Between the acidic SnF(2) and the 1% AmF solutions no significant differences could be detected.
CONCLUSION
At the same concentrations, acidic SnF(2) and AmF may be more effective than NaF to protect enamel against erosion.
This study aimed to compare the effects 0.5% and 1% sodium, amine and stannous fluoride at different pH on enamel erosion in vitro.
METHODS
Bovine enamel samples were submitted to a cyclic de- and remineralisation for 3 days. Each day, the samples were exposed for 120 min to pooled human saliva and subsequently treated with one of the fluoride solutions for 3 min: amine fluoride (AmF, 0.5% and 1% F(-)), sodium fluoride (NaF, 0.5% and 1% F(-)), each at pH 3.9 and 7.0, and stannous fluoride (SnF(2), 0.5% and 1% F(-)), at pH: 3.9. Additionally, two groups were treated with fluoride-free placebo solutions (pH: 3.9 and 7.0) and one group served as control (no fluoridation). Ten specimens each group were inserted in a so-called artificial mouth and eroded six times daily with hydrochloric acid (pH 2.6) for 90 s each intermitted by exposure to artificial saliva (1h). After 3 days, enamel loss was analyzed profilometrically and evaluated statistically by ANOVA.
RESULTS
Only the acidic 0.5% and 1% SnF(2) and 1% AmF solutions were able to reduce erosive enamel loss significantly, while all other solutions and placebos did not differ significantly from the control. Between the acidic SnF(2) and the 1% AmF solutions no significant differences could be detected.
CONCLUSION
At the same concentrations, acidic SnF(2) and AmF may be more effective than NaF to protect enamel against erosion.
- Language
-
- English
- Open access status
- green
- Identifiers
-
- DOI 10.1016/j.jdent.2009.03.020
- PMID 19403228
- Persistent URL
- https://sonar.ch/global/documents/253214
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