Paraneoplastic hyperthyroidism.
- 2012-06-13
Published in:
- BMJ case reports. - 2011
Adult
Antineoplastic Agents
Choriocarcinoma
Chorionic Gonadotropin
Diagnosis, Differential
Humans
Hyperthyroidism
Male
Neoplasms, Germ Cell and Embryonal
English
The authors describe a 31-year-old male with a metastatic germ cell tumour and massively elevated human chorionic gonadotrophin (HCG) levels who presented with hyperthyroidism. As HCG is structurally closely related to thyroid stimulating hormone (TSH), it can activate the TSH receptor; grossly elevated levels may result in hyperthyroidism. After initiation of chemotherapy, HCG levels decreased and hyperthyroidism resolved.
- Language
-
- English
- Open access status
- green
- Identifiers
-
- DOI 10.1136/bcr.04.2011.4163
- PMID 22688478
- Persistent URL
- https://sonar.ch/global/documents/262965
Statistics
Document views: 32
File downloads:
- Full-text: 0