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In vivo confirmation of hydration-induced changes in human-skin thickness, roughness and interaction with the environment.

  • Dąbrowska AK Laboratory for Protection and Physiology, Empa, Swiss Federal Laboratories for Materials Science and Technology, CH-9014 St. Gallen, Switzerland and Laboratory for Surface Science and Technology, Department of Materials, ETH Zürich, CH-8093 Zürich, Switzerland.
  • Adlhart C Institute of Chemistry and Biotechnology, Zurich University of Applied Sciences, ZHAW, CH-8820 Wädenswil, Switzerland.
  • Spano F Laboratory for Protection and Physiology, Empa, Swiss Federal Laboratories for Materials Science and Technology, CH-9014 St. Gallen, Switzerland.
  • Rotaru GM Laboratory for Protection and Physiology, Empa, Swiss Federal Laboratories for Materials Science and Technology, CH-9014 St. Gallen, Switzerland and Center for X-ray Analytics, Empa, Swiss Federal Laboratories for Materials Science and Technology, CH-8600 Dübendorf, Switzerland.
  • Derler S Laboratory for Protection and Physiology, Empa, Swiss Federal Laboratories for Materials Science and Technology, CH-9014 St. Gallen, Switzerland.
  • Zhai L Laboratory for Protection and Physiology, Empa, Swiss Federal Laboratories for Materials Science and Technology, CH-9014 St. Gallen, Switzerland and Fashion Institute, Protective Clothing Research Center, Donghua University, 200051 Shanghai, China.
  • Spencer ND Department of Materials, Laboratory for Surface Science and Technology, ETH Zürich, CH-8093 Zürich, Switzerland.
  • Rossi RM Laboratory for Protection and Physiology, Empa, Swiss Federal Laboratories for Materials Science and Technology, CH-9014 St. Gallen, Switzerland.
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  • 2016-09-17
Published in:
  • Biointerphases. - 2016
Fluid Therapy
Humans
Microscopy, Confocal
Skin
Skin Physiological Phenomena
Spectrum Analysis, Raman
Surface Properties
English The skin properties, structure, and performance can be influenced by many internal and external factors, such as age, gender, lifestyle, skin diseases, and a hydration level that can vary in relation to the environment. The aim of this work was to demonstrate the multifaceted influence of water on human skin through a combination of in vivo confocal Raman spectroscopy and images of volar-forearm skin captured with the laser scanning confocal microscopy. By means of this pilot study, the authors have both qualitatively and quantitatively studied the influence of changing the depth-dependent hydration level of the stratum corneum (SC) on the real contact area, surface roughness, and the dimensions of the primary lines and presented a new method for characterizing the contact area for different states of the skin. The hydration level of the skin and the thickness of the SC increased significantly due to uptake of moisture derived from liquid water or, to a much lesser extent, from humidity present in the environment. Hydrated skin was smoother and exhibited higher real contact area values. The highest rates of water uptake were observed for the upper few micrometers of skin and for short exposure times.
Language
  • English
Open access status
hybrid
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Persistent URL
https://sonar.ch/global/documents/265836
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