EXPERIMENTAL VALIDATION OF A MEAN FILED MODEL OF MINERALIZED COLLAGEN FIBER ARRAYS AT TWO LEVELS OF HIERARCHY
Journal article

EXPERIMENTAL VALIDATION OF A MEAN FILED MODEL OF MINERALIZED COLLAGEN FIBER ARRAYS AT TWO LEVELS OF HIERARCHY

  • SPIESZ, EWA M. Department of Applied Physics, Eindhoven University of Technology, P.O. Box 513, NL-5600 MB Eindhoven, The Netherlands
  • REISINGER, ANDREAS G. Institute of Lightweight Design and Structural Biomechanics, Vienna University of Technology, Gusshausstrasse 27-29, A-1040 Vienna, Austria
  • ROSCHGER, PAUL Ludwig Boltzmann Institute of Osteology at the Hanusch Hospital of WGKK and AUVA Trauma Centre Meidling, 1st Med. Dept., Hanusch Hospital, Heinrich Collin Str. 30, 1140 Vienna, Austria
  • ZYSSET, PHILIPPE K. Institute for Surgical Technology & Biomechanics, University of Bern, Stauffacherstrasse 78, CH-3014 Bern, Switzerland
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  • 2014-3-10
Published in:
  • Journal of Mechanics in Medicine and Biology. - World Scientific Pub Co Pte Lt. - 2014, vol. 14, no. 02, p. 1450013
English In the course of this study, stiffness of a fibril array of mineralized collagen fibrils modeled with a mean field method was validated experimentally at site-matched two levels of tissue hierarchy using mineralized turkey leg tendons (MTLT). The applied modeling approaches allowed to model the properties of this unidirectional tissue from nanoscale (mineralized collagen fibrils) to macroscale (mineralized tendon). At the microlevel, the indentation moduli obtained with a mean field homogenization scheme were compared to the experimental ones obtained with microindentation. At the macrolevel, the macroscopic stiffness predicted with micro finite element (μFE) models was compared to the experimental stiffness measured with uniaxial tensile tests. Elastic properties of the elements in μFE models were injected from the mean field model or two-directional microindentations. Quantitatively, the indentation moduli can be properly predicted with the mean-field models. Local stiffness trends within specific tissue morphologies are very weak, suggesting additional factors responsible for the stiffness variations. At macrolevel, the μFE models underestimate the macroscopic stiffness, as compared to tensile tests, but the correlations are strong.
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  • English
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https://sonar.ch/global/documents/268477
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