An Analysis of Two Genome-wide Association Meta-analyses Identifies a New Locus for Broad Depression Phenotype.

• Direk N Department of Epidemiology, Erasmus University Medical Center, Rotterdam; Department of Psychiatry, Dokuz Eylul University, Izmir, Turkey.
• Williams S Department of Genetics, Genomic Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
• Smith JA Department of Epidemiology, University of Michigan, Ann Arbor, Michigan.
• Ripke S Stanley Center for Psychiatric Research, The Broad Institute of Harvard and MIT, Cambridge; Analytic and Translational Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston; Department of Psychiatry and Psychotherapy, Charité, Campus Mitte, Berlin.
• Air T Discipline of Psychiatry, School of Medicine, University of Adelaide, Adelaide, South Australia.
• Amare AT Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen; Discipline of Psychiatry, School of Medicine, University of Adelaide, Adelaide, South Australia.
• Amin N Genetic Epidemiology Unit, Erasmus University Medical Center, Rotterdam.
• Baune BT Discipline of Psychiatry, School of Medicine, University of Adelaide, Adelaide, South Australia.
• Bennett DA Rush Alzheimer's Disease Center & Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois.
• Blackwood DHR Division of Psychiatry, University of Edinburgh, Edinburgh.
• Boomsma D Department of Biological Psychology, VU University, Amsterdam, The Netherlands.
• Breen G MRC Social, Genetic & Developmental Psychiatry Centre Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London.
• Buttenschøn HN Translational Neuropsychiatry Unit, Department of Clinical Medicine, Aarhus; The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus.
• Byrne EM Queensland Brain Institute, University of Queensland, St. Lucia, Queensland.
• Børglum AD Department of Biomedicine and Centre for Integrative Sequencing, Aarhus University, Aarhus; The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus.
• Castelao E Department of Psychiatry, Lausanne University Hospital, Lausanne.
• Cichon S Institute of Human Genetics, University of Bonn, Bonn; Department of Genomics, Life & Brain Center, Bonn; Institute of Neuroscience and Medicine, Research Centre Jülich, Jülich; Division of Medical Genetics, Department of Biomedicine, University of Basel, Basel, Switzerland.
• Clarke TK Division of Psychiatry, University of Edinburgh, Edinburgh.
• Cornelis MC Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
• Dannlowski U Department of Psychiatry and Psychotherapy, University of Münster, Münster.
• De Jager PL Program in Medical and Population Genetics, The Broad Institute of Harvard and MIT, Cambridge; Department of Neurology, Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Neurology, Harvard Medical School, Boston.
• Demirkan A Genetic Epidemiology Unit, Erasmus University Medical Center, Rotterdam.
• Domenici E Roche Pharmaceutical Research and Early Development, Neuroscience, Ophthalmology and Rare Diseases Discovery & Translational Medicine Area, Roche Innovation Center Basel, F Hoffman-La Roche Ltd., Basel, Switzerland; Centre for Integrative Biology, University of Trento, Trento, Italy.
• van Duijn CM Genetic Epidemiology Unit, Erasmus University Medical Center, Rotterdam.
• Dunn EC Stanley Center for Psychiatric Research, The Broad Institute of Harvard and MIT, Cambridge; Psychiatric and Neurodevelopmental Genetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, Boston; Department of Psychiatry, Harvard Medical School, Boston.
• Eriksson JG National Institute for Health and Welfare, Department of Chronic Disease Prevention, Helsinki; Department of General Practice and Primary Health Care, University of Helsinki, Helsinki; Unit of General Practice, Helsinki University Central Hospital, Helsinki; Folkhalsan Research Centre, Helsinki; Vasa Central Hospital, Vasa, Finland.
• Esko T Program in Medical and Populational Genetics, The Broad Institute of Harvard and MIT, Cambridge; Division of Endocrinology, Boston Children's Hospital, Cambridge; Department of Genetics, Harvard Medical School, Boston; Estonian Genome Center, University of Tartu, Tartu, Estonia.
• Faul JD Institute for Social Research, University of Michigan, Ann Arbor, Michigan.
• Ferrucci L Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland.
• Fornage M Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, Texas.
• de Geus E Department of Biological Psychology, VU University, Amsterdam, The Netherlands.
• Gill M Department of Psychiatry, Trinity Centre for Health Science, Dublin, Ireland.
• Gordon SD QIMR Berghofer Medical Research Institute, Brisbane.
• Grabe HJ Department of Psychiatry and Psychotherapy, Helios Hospital Stralsund, Munich; Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Munich; German Center for Neurodegenerative Diseases, Site Rostock/Greifswald, Munich.
• van Grootheest G Department of Psychiatry, Neuroscience Campus Amsterdam and EMGO Institute of Health and Care Research, VU University, Amsterdam, The Netherlands.
• Hamilton SP Department of Psychiatry, Kaiser Permanente San Francisco Medical Center, San Francisco.
• Hartman CA Department of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen.
• Heath AC Department of Psychiatry, Washington University, St. Louis, Missouri.
• Hek K Department of Epidemiology, Erasmus University Medical Center, Rotterdam; Department of Psychiatry, Erasmus University Medical Center, Rotterdam.
• Hofman A Department of Epidemiology, Erasmus University Medical Center, Rotterdam.
• Homuth G Interfaculty Institute for Genetics and Functional Genomics, University of Greifswald, Munich.
• Horn C Roche Pharmaceutical Research and Early Development, Neuroscience, Ophthalmology and Rare Diseases Discovery & Translational Medicine Area, Roche Innovation Center Basel, F Hoffman-La Roche Ltd., Basel, Switzerland.
• Jan Hottenga J Department of Biological Psychology, VU University, Amsterdam, The Netherlands.
• Kardia SLR Department of Epidemiology, University of Michigan, Ann Arbor, Michigan.
• Kloiber S Max Planck Institute of Psychiatry, Munich.
• Koenen K Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York.
• Kutalik Z Institute of Social and Preventive Medicine, Centre Hospitalier Universitaire Vaudois, Lausanne.
• Ladwig KH Department of Psychosomatic Medicine and Psychotherapy, Klinikum rechts der Isar, Technische Universität München, Munich; Institute of Epidemiology II, Mental Health Research Unit, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg.
• Lahti J Folkhalsan Research Centre, Helsinki; Institute of Behavioural Sciences, University of Helsinki, Helsinki.
• Levinson DF Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, California.
• Lewis CM MRC Social, Genetic & Developmental Psychiatry Centre Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London.
• Lewis G Division of Psychiatry, University College London, London.
• Li QS Janssen Research & Development LLC, New Brunswick, New Jersey.
• Llewellyn DJ University of Exeter Medical School, Exeter.
• Lucae S Max Planck Institute of Psychiatry, Munich.
• Lunetta KL Department of Biostatistics, Boston University School of Public Health, Framingham, Massachusetts; Boston University and National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, Massachusetts.
• MacIntyre DJ Division of Psychiatry, University of Edinburgh, Edinburgh.
• Madden P Department of Psychiatry, Washington University, St. Louis, Missouri.
• Martin NG QIMR Berghofer Medical Research Institute, Brisbane.
• McIntosh AM Division of Psychiatry, University of Edinburgh, Edinburgh.
• Metspalu A Estonian Genome Center, University of Tartu, Tartu, Estonia; Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia.
• Milaneschi Y Department of Psychiatry, Neuroscience Campus Amsterdam and EMGO Institute of Health and Care Research, VU University, Amsterdam, The Netherlands.
• Montgomery GW QIMR Berghofer Medical Research Institute, Brisbane.
• Mors O The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus; Research Department P, Aarhus University Hospital, Risskov, Denmark.
• Mosley TH Department of Medicine, University of Mississippi Medical Center, Jackson, Mississippi.
• Murabito JM Department of Medicine, Section of General Internal Medicine, Boston University School of Medicine, Boston; Boston University and National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, Massachusetts.
• Müller-Myhsok B Max Planck Institute of Psychiatry, Munich; Munich Cluster for Systems Neurology, Munich; University of Liverpool, Institute of Translational Medicine, Liverpool.
• Nöthen MM Institute of Human Genetics, University of Bonn, Bonn; Department of Genomics, Life & Brain Center, Bonn.
• Nyholt DR QIMR Berghofer Medical Research Institute, Brisbane; Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland.
• O'Donovan MC MRC Centre for Neuropsychiatric Genetics and Genomics, Institute of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff, United Kingdom.
• Penninx BW Department of Psychiatry, Neuroscience Campus Amsterdam and EMGO Institute of Health and Care Research, VU University, Amsterdam, The Netherlands.
• Pergadia ML Department of Psychiatry, Washington University, St. Louis, Missouri; Charles E. Schmidt College of Medicine, Florida Atlantic University, Boca Raton, Florida.
• Perlis R Center for Experimental Drugs and Diagnostics, Massachusetts General Hospital and Harvard Medical School, Boston.
• Potash JB Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, Iowa.
• Preisig M Department of Psychiatry, Lausanne University Hospital, Lausanne.
• Purcell SM Division of Psychiatric Genomics, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York.
• Quiroz JA Solid GT, Boston; Roche Pharmaceutical Research and Early Development, Neuroscience, Ophthalmology and Rare Diseases Discovery & Translational Medicine Area, Roche Innovation Center Basel, F Hoffman-La Roche Ltd., Basel, Switzerland.
• Räikkönen K Institute of Behavioural Sciences, University of Helsinki, Helsinki.
• Rice JP Department of Psychiatry, Washington University, St. Louis, Missouri.
• Rietschel M Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim/Heidelberg University, Mannheim.
• Rivera M MRC Social, Genetic & Developmental Psychiatry Centre Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London; CIBERSAM-Universidad de Granada, Hospitales Universitarios de Granada/Universidad de Granada, Granada, Spain; Instituto de Investigación Biosanitaria ibs.GRANADA, Hospitales Universitarios de Granada/Universidad de Granada, Granada, Spain.
• Schulze TG Institute of Psychiatric Phenomics and Genomics, Ludwig-Maximilians-University, Munich; Department of Psychiatry and Psychotherapy, University of Göttingen, Göttingen, Germany.
• Shi J Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.
• Shyn S Group Health, Seattle, Washington.
• Sinnamon GC Department of Psychiatry and Psychiatric Neuroscience, School of Medicine and Dentistry, James Cook University, Townsville, Queensland, Australia.
• Smit JH Department of Psychiatry, Neuroscience Campus Amsterdam and EMGO Institute of Health and Care Research, VU University, Amsterdam, The Netherlands.
• Smoller JW Stanley Center for Psychiatric Research, The Broad Institute of Harvard and MIT, Cambridge; Psychiatric and Neurodevelopmental Genetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, Boston; Department of Psychiatry, Harvard Medical School, Boston.
• Snieder H Unit of Genetic Epidemiology & Bioinformatics, University Medical Center Groningen, University of Groningen, Groningen.
• Tanaka T Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland.
• Tansey KE MRC Centre for Neuropsychiatric Genetics and Genomics, Institute of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff, United Kingdom.
• Teumer A Institute for Community Medicine, University Medicine Greifswald, Greifswald, Munich.
• Uher R MRC Social, Genetic & Developmental Psychiatry Centre Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London; Dalhousie University, Halifax, Nova Scotia, Canada.
• Umbricht D Roche Pharmaceutical Research and Early Development, Neuroscience, Ophthalmology and Rare Diseases Discovery & Translational Medicine Area, Roche Innovation Center Basel, F Hoffman-La Roche Ltd., Basel, Switzerland.
• Van der Auwera S Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Munich; German Center for Neurodegenerative Diseases, Site Rostock/Greifswald, Munich.
• Ware EB Department of Epidemiology, University of Michigan, Ann Arbor, Michigan; Institute for Social Research, University of Michigan, Ann Arbor, Michigan.
• Weir DR Institute for Social Research, University of Michigan, Ann Arbor, Michigan.
• Weissman MM College of Physicians and Surgeons, Columbia University and New York State Psychiatric Institute, New York, New York.
• Willemsen G Department of Biological Psychology, VU University, Amsterdam, The Netherlands.
• Yang J Rush Alzheimer's Disease Center & Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois.
• Zhao W Department of Epidemiology, University of Michigan, Ann Arbor, Michigan.
• Tiemeier H Department of Epidemiology, Erasmus University Medical Center, Rotterdam; Department of Psychiatry, Erasmus University Medical Center, Rotterdam. Electronic address: h.tiemeier@erasmusmc.nl.
• Sullivan PF Department of Psychiatry, Genomic Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; Center for Psychiatric Genomics, Genomic Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Sweden.

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CHARGE consortium

Depressive symptoms

FHIT gene

Genome-wide association study

Major depressive disorder

Psychiatric Genomics Consortium

Acid Anhydride Hydrolases

Depression

Depressive Disorder

European Continental Ancestry Group

Genetic Loci

Genetic Predisposition to Disease

Genome-Wide Association Study

Humans

Neoplasm Proteins

Phenotype