Journal article

Human Adult Neurogenesis: Evidence and Remaining Questions.

  • Kempermann G German Center for Neurodegenerative Diseases (DZNE) Dresden and CRTD (Center for Regenerative Therapies Dresden), Technische Universität Dresden, Dresden, Germany. Electronic address: gerd.kempermann@dzne.de.
  • Gage FH Laboratory of Genetics, The Salk Institute for Biological Studies, La Jolla, CA, USA. Electronic address: gage@salk.edu.
  • Aigner L Institute of Molecular Regenerative Medicine, Spinal Cord Injury and Tissue Regeneration Center Salzburg, Paracelsus Medical University, Salzburg, Austria.
  • Song H Department of Neuroscience, University of Pennsylvania, Philadelphia, PA, USA.
  • Curtis MA Department of Anatomy and Medical Imaging and Centre for Brain Research, The University of Auckland, Auckland, New Zealand.
  • Thuret S King's College London, Institute of Psychiatry, Psychology & Neuroscience, Department of Basic and Clinical Neuroscience, London, UK.
  • Kuhn HG University of Gothenburg, Institute for Neuroscience and Physiology, Section for Clinical Neuroscience, Gothenburg, Sweden; Charité - Universitätsmedizin Berlin, Neurocure Cluster of Excellence, Berlin, Germany.
  • Jessberger S HiFo / Brain Research Institute, University of Zurich, Zurich, Switzerland.
  • Frankland PW Program in Neuroscience and Mental Health, Hospital for Sick Children, Toronto, ON M5GOA4, Canada.
  • Cameron HA Section on Neuroplasticity, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA.
  • Gould E Princeton Neuroscience Institute, Princeton University, Princeton, NJ, USA.
  • Hen R Departments of Neuroscience and Psychiatry, Columbia University, New York, NY, USA.
  • Abrous DN Neurocentre Magendie, INSERM U1215, Bordeaux, France.
  • Toni N Lausanne University Hospital, Department of Psychiatry, Center for Psychiatric Neurosciences, Lausanne, Switzerland.
  • Schinder AF Neuronal Plasticity Lab, Leloir Institute - CONICET, Buenos Aires, Argentina.
  • Zhao X Waisman Center and Department of Neuroscience, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, USA.
  • Lucassen PJ Brain Plasticity group, Swammerdam Institute for Life Sciences, Center for Neuroscience, University of Amsterdam, the Netherlands.
  • Frisén J Department of Cell and Molecular Biology, Karolinska Institute, Stockholm, Sweden. Electronic address: jonas.frisén@ki.se.
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  • 2018-04-24
Published in:
  • Cell stem cell. - 2018
English Renewed discussion about whether or not adult neurogenesis exists in the human hippocampus, and the nature and strength of the supporting evidence, has been reignited by two prominently published reports with opposite conclusions. Here, we summarize the state of the field and argue that there is currently no reason to abandon the idea that adult-generated neurons make important functional contributions to neural plasticity and cognition across the human lifespan.
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  • English
Open access status
bronze
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https://sonar.ch/global/documents/271312
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