Journal article
Chlamydia trachomatis and chlamydia-like bacteria: new enemies of human pregnancies.
- Ammerdorffer A aMaterno-fetal and Obstetrics Research Unit, Department of Obstetrics and Gynecology, Maternity, University Hospital bCenter for Research on Intracellular Bacteria, Institute of Microbiology, Faculty of Biology and Medicine, University of Lausanne and University Hospital cInfectious Disease Service, University Hospital, Lausanne, Switzerland.
- Stojanov M
- Greub G
- Baud D
- 2017-03-18
Published in:
- Current opinion in infectious diseases. - 2017
Abortion, Septic
Chlamydia Infections
Chlamydia trachomatis
Chlamydiales
Female
Humans
Pregnancy
Pregnancy Outcome
English
PURPOSE OF REVIEW
This review provides an update on the roles of Chlamydia trachomatis and the related Waddlia chondrophila and Parachlamydia acanthamoebae in miscarriage, stillbirths and preterm labour in humans. A broad audience, including microbiologist, infectiologists, obstetricians and gynaecologists, should be aware of the potential threat of these Chlamydiales for human reproduction.
RECENT FINDINGS
Despite increasing laboratory techniques and possibilities to perform diagnostic tests, the cause of miscarriage is only identified in 50% of the cases. Intracellular bacteria, such as C. trachomatis and Chlamydia-related bacteria, are difficult to detect in routine clinical samples and could represent possible agents of miscarriages. C. trachomatis is considered the world largest sexual transmitted bacterial agent and is associated with adverse pregnancy outcome in human. In the last decade Chlamydia-like organisms, such as W. chondrophila and P. acanthamoebae, have also been associated with adverse pregnancy outcomes in human and/or animals.
SUMMARY
We review here the current evidences for a pathogenic role in humans, the diagnostic approaches and possible treatment options of C. trachomatis, W. chondrophila and P. acanthamoebae.
This review provides an update on the roles of Chlamydia trachomatis and the related Waddlia chondrophila and Parachlamydia acanthamoebae in miscarriage, stillbirths and preterm labour in humans. A broad audience, including microbiologist, infectiologists, obstetricians and gynaecologists, should be aware of the potential threat of these Chlamydiales for human reproduction.
RECENT FINDINGS
Despite increasing laboratory techniques and possibilities to perform diagnostic tests, the cause of miscarriage is only identified in 50% of the cases. Intracellular bacteria, such as C. trachomatis and Chlamydia-related bacteria, are difficult to detect in routine clinical samples and could represent possible agents of miscarriages. C. trachomatis is considered the world largest sexual transmitted bacterial agent and is associated with adverse pregnancy outcome in human. In the last decade Chlamydia-like organisms, such as W. chondrophila and P. acanthamoebae, have also been associated with adverse pregnancy outcomes in human and/or animals.
SUMMARY
We review here the current evidences for a pathogenic role in humans, the diagnostic approaches and possible treatment options of C. trachomatis, W. chondrophila and P. acanthamoebae.
- Language
-
- English
- Open access status
- closed
- Identifiers
-
- DOI 10.1097/QCO.0000000000000369
- PMID 28306562
- Persistent URL
- https://sonar.ch/global/documents/27573
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