Pathogenesis and potential strategies for prevention and treatment of septic shock: an update.
- Glauser MP Department of Internal Medicine, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.
- Heumann D
- Baumgartner JD
- Cohen J
- 1994-02-01
Published in:
- Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. - 1994
English
Septic shock is mediated by complex interactions of cells, cytokines, and humoral pathways. Clinical therapeutic strategies aimed at inhibiting selected pathways have been efficacious in subsets of patients. Experimental studies focusing on the activities of single cytokines have contributed to the understanding of the complex pathophysiology of septic shock. More precise delineation of the roles of each mechanism contributing to pathogenesis will permit the identification of subsets of patients who might benefit from particular therapeutic strategies and will guide the development of additional approaches to prevention and treatment.
- Language
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- English
- Open access status
- green
- Identifiers
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- DOI 10.1093/clinids/18.supplement_2.s205
- PMID 8148464
- Persistent URL
- https://sonar.ch/global/documents/277794
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