Psoriasis Caught in the NET.
- Di Domizio J Department of Dermatology, Lausanne University Hospital CHUV, Lausanne, Switzerland.
- Gilliet M Department of Dermatology, Lausanne University Hospital CHUV, Lausanne, Switzerland. Electronic address: michel.gilliet@chuv.ch.
- 2019-06-25
Published in:
- The Journal of investigative dermatology. - 2019
Adaptor Proteins, Signal Transducing
Extracellular Traps
Genotype
Humans
Neutrophils
Psoriasis
Th17 Cells
Tumor Necrosis Factor Receptor-Associated Peptides and Proteins
English
A report in the June 2019 issue of the Journal of Investigative Dermatology reveals a role of neutrophil extracellular traps (NETs) in the induction of T helper type 17 cell responses and shows the relevance of this pathway in patients with psoriasis carrying a common risk variant in the TRAF3IP2 gene (Lambert et al., 2019). This work provides a new piece to the puzzle that links neutrophils to the T helper type 17-mediated pathogenesis of psoriasis.
- Language
-
- English
- Open access status
- bronze
- Identifiers
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- DOI 10.1016/j.jid.2019.04.020
- PMID 31230639
- Persistent URL
- https://sonar.ch/global/documents/278066
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