Journal article
Paired-eye comparison of corneal endothelial cell counts after unilateral iris-claw phakic intraocular lens implantation.
- Morral M From Instituto de Microcirugia Ocular (Morral, Güell, Elies, Gris, Manero) and Universitat Autonoma de Barcelona (Güell), Barcelona, Spain; European School for Advanced Studies in Ophthalmology (Güell), Lugano, Switzerland; Cornea and Refractive Surgery Department (El Husseiny), Research Institute of Ophthalmology, Giza, Egypt. Electronic address: merce.morral@gmail.com.
- Güell JL From Instituto de Microcirugia Ocular (Morral, Güell, Elies, Gris, Manero) and Universitat Autonoma de Barcelona (Güell), Barcelona, Spain; European School for Advanced Studies in Ophthalmology (Güell), Lugano, Switzerland; Cornea and Refractive Surgery Department (El Husseiny), Research Institute of Ophthalmology, Giza, Egypt.
- El Husseiny MA From Instituto de Microcirugia Ocular (Morral, Güell, Elies, Gris, Manero) and Universitat Autonoma de Barcelona (Güell), Barcelona, Spain; European School for Advanced Studies in Ophthalmology (Güell), Lugano, Switzerland; Cornea and Refractive Surgery Department (El Husseiny), Research Institute of Ophthalmology, Giza, Egypt.
- Elies D From Instituto de Microcirugia Ocular (Morral, Güell, Elies, Gris, Manero) and Universitat Autonoma de Barcelona (Güell), Barcelona, Spain; European School for Advanced Studies in Ophthalmology (Güell), Lugano, Switzerland; Cornea and Refractive Surgery Department (El Husseiny), Research Institute of Ophthalmology, Giza, Egypt.
- Gris O From Instituto de Microcirugia Ocular (Morral, Güell, Elies, Gris, Manero) and Universitat Autonoma de Barcelona (Güell), Barcelona, Spain; European School for Advanced Studies in Ophthalmology (Güell), Lugano, Switzerland; Cornea and Refractive Surgery Department (El Husseiny), Research Institute of Ophthalmology, Giza, Egypt.
- Manero F From Instituto de Microcirugia Ocular (Morral, Güell, Elies, Gris, Manero) and Universitat Autonoma de Barcelona (Güell), Barcelona, Spain; European School for Advanced Studies in Ophthalmology (Güell), Lugano, Switzerland; Cornea and Refractive Surgery Department (El Husseiny), Research Institute of Ophthalmology, Giza, Egypt.
- 2016-03-08
Published in:
- Journal of cataract and refractive surgery. - 2016
Adult
Cataract Extraction
Cell Count
Corneal Endothelial Cell Loss
Endothelium, Corneal
Female
Humans
Iris
Lens Implantation, Intraocular
Male
Middle Aged
Phakic Intraocular Lenses
Refraction, Ocular
Refractive Surgical Procedures
Retrospective Studies
Visual Acuity
Young Adult
English
PURPOSE
To compare the corneal endothelial cell density (ECD) after unilateral iris-claw phakic intraocular lens (pIOL) implantation.
SETTING
Instituto de Microcirugia Ocular, Barcelona, Spain.
DESIGN
Retrospective interventional nonrandomized paired-eye comparison.
METHODS
Patients who had pIOL implantation in 1 eye and corneal refractive surgery (Group 1) or no surgery in the fellow eye (Group 2) between 1998 and 2010 were included. The main outcome measures were central corneal ECD and the percentage of corneal endothelial cell loss. Secondary outcome measures were uncorrected distance visual acuity, corrected distance visual acuity, manifest refraction, and complications. Outcome measures were analyzed 1, 5, and 10 years postoperatively.
RESULTS
Both groups comprised 29 patients. Ten years after surgery, the mean endothelial cell loss was 6.41% ± 8.02% (SD) (Group 1, iris-claw pIOLs), 5.59% ± 5.98% (Group 1, corneal refractive surgery), 7.84% ± 6.83% (Group 2, iris-claw pIOLs), and 6.74% ± 3.97% (Group 2, no surgery). No significant endothelial cell loss was observed after pIOL implantation or corneal refractive surgery at any timepoint (P > .05). No significant differences were observed in the percentage of endothelial cell loss between the groups (P > .05).
CONCLUSIONS
Iris-claw pIOL implantation did not produce significant corneal endothelial cell loss up to 10 years after surgery compared with corneal refractive surgery and unoperated eyes when strict inclusion criteria were met.
FINANCIAL DISCLOSURE
Dr. Güell is a consultant to Ophtec BV and Carl Zeiss Meditec AG. No other author has a financial or proprietary interest in any material or method mentioned.
To compare the corneal endothelial cell density (ECD) after unilateral iris-claw phakic intraocular lens (pIOL) implantation.
SETTING
Instituto de Microcirugia Ocular, Barcelona, Spain.
DESIGN
Retrospective interventional nonrandomized paired-eye comparison.
METHODS
Patients who had pIOL implantation in 1 eye and corneal refractive surgery (Group 1) or no surgery in the fellow eye (Group 2) between 1998 and 2010 were included. The main outcome measures were central corneal ECD and the percentage of corneal endothelial cell loss. Secondary outcome measures were uncorrected distance visual acuity, corrected distance visual acuity, manifest refraction, and complications. Outcome measures were analyzed 1, 5, and 10 years postoperatively.
RESULTS
Both groups comprised 29 patients. Ten years after surgery, the mean endothelial cell loss was 6.41% ± 8.02% (SD) (Group 1, iris-claw pIOLs), 5.59% ± 5.98% (Group 1, corneal refractive surgery), 7.84% ± 6.83% (Group 2, iris-claw pIOLs), and 6.74% ± 3.97% (Group 2, no surgery). No significant endothelial cell loss was observed after pIOL implantation or corneal refractive surgery at any timepoint (P > .05). No significant differences were observed in the percentage of endothelial cell loss between the groups (P > .05).
CONCLUSIONS
Iris-claw pIOL implantation did not produce significant corneal endothelial cell loss up to 10 years after surgery compared with corneal refractive surgery and unoperated eyes when strict inclusion criteria were met.
FINANCIAL DISCLOSURE
Dr. Güell is a consultant to Ophtec BV and Carl Zeiss Meditec AG. No other author has a financial or proprietary interest in any material or method mentioned.
- Language
-
- English
- Open access status
- closed
- Identifiers
-
- DOI 10.1016/j.jcrs.2015.08.018
- PMID 26948786
- Persistent URL
- https://sonar.ch/global/documents/278897
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