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Role of isotope scan, including positron emission tomography/computed tomography, in nodular goitre.
Journal article

Role of isotope scan, including positron emission tomography/computed tomography, in nodular goitre.

  • Giovanella L Department of Nuclear Medicine and PET/CT Centre, Oncology Institute of Southern Switzerland, Bellinzona, Switzerland; EOC Competence Centre for Thyroid Diseases, Oncology Institute of Southern Switzerland, Bellinzona, Switzerland. Electronic address: luca.giovanella@eoc.ch.
  • Ceriani L Department of Nuclear Medicine and PET/CT Centre, Oncology Institute of Southern Switzerland, Bellinzona, Switzerland; EOC Competence Centre for Thyroid Diseases, Oncology Institute of Southern Switzerland, Bellinzona, Switzerland.
  • Treglia G Department of Nuclear Medicine and PET/CT Centre, Oncology Institute of Southern Switzerland, Bellinzona, Switzerland; EOC Competence Centre for Thyroid Diseases, Oncology Institute of Southern Switzerland, Bellinzona, Switzerland.
  • 2014-07-23
Published in:
  • Best practice & research. Clinical endocrinology & metabolism. - 2014
nodular goitre
nuclear medicine
positron emission tomography
scintigraphy
Fluorodeoxyglucose F18
Goiter, Nodular
Humans
Iodine Radioisotopes
Molecular Imaging
Multimodal Imaging
Positron-Emission Tomography
Predictive Value of Tests
Radioactive Tracers
Technetium
Thyroid Nodule
Tomography, Emission-Computed
English Nuclear medicine techniques were first used in clinical practice for diagnosing and treating thyroid diseases in the 1950s, and are still an integral part of thyroid nodules work-up. Thyroid imaging with iodine or iodine-analogue isotopes is the only examination able to prove the presence of autonomously functioning thyroid tissue, which excludes malignancy with a high probability. In addition, a thyroid scan with technetium-99m-methoxyisobutylisonitrile is able to avoid unnecessary surgical procedures for cytologically inconclusive thyroid nodules, as confirmed by meta-analysis and cost-effectiveness studies. Finally, positron emission tomography alone, and positron emission tomography combined with computed tomography scans with (18)F-fluoro-2-deoxy-d-glucose are also promising for diagnosing thyroid diseases, but further studies are needed before introducing them to clinical practice.
Language
  • English
Open access status
closed
Identifiers
Persistent URL
https://sonar.ch/global/documents/279173
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