Evidence of a genetic basis of Morgagni-Stewart-Morel syndrome. A case report of identical twins.
- Koller MF Division of Psychiatry Research, University of Zurich, Zurich, Switzerland. miko1@gmx.ch
- Papassotiropoulos A
- Henke K
- Behrends B
- Noda S
- Kratzer A
- Hock C
- Hofmann M
- 2006-08-16
Published in:
- Neuro-degenerative diseases. - 2005
Aged
Aged, 80 and over
Diseases in Twins
Female
Humans
Hyperostosis Frontalis Interna
Magnetic Resonance Imaging
Twin Studies as Topic
Twins, Monozygotic
English
We report two 71-year-old female monozygotic twins presenting with advanced hyperostosis frontalis interna, obesity, shortness and cognitive impairment. They both have suffered from generalized seizures since their early adulthood. Moreover, the patients showed some additional conditions only occurring in one individual or the other such as migraine, marked recurrent depressive disorder or polyarthrosis. The symptoms common to both twins appear to correspond to the Morgagni-Stewart-Morel syndrome and indicate a genetic basis of this disorder as these features occur in genetically identical patients.
- Language
-
- English
- Open access status
- green
- Identifiers
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- DOI 10.1159/000089284
- PMID 16909048
- Persistent URL
- https://sonar.ch/global/documents/280437
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