Journal article
Behavioral alterations in reward system function: the role of childhood maltreatment and psychopathology.
- Guyer AE Drs. Guyer, Pine, and Ernst are with the Mood and Anxiety Program, National Institute of Mental Health, Bethesda, MD; Dr. Kaufman is with the Department of Psychiatry, Yale University, New Haven, CT; Ms. Hodgdon is with the Department of Psychology, Temple University, Philadelphia; Ms. Masten is with the Department of Psychology, University of California, Los Angeles; and Ms. Jazbec is with the Department of Psychology, University of Zurich, Zurich, Switzerland. Electronic address: amandaguyer@mail.nih.gov.
- Kaufman J Drs. Guyer, Pine, and Ernst are with the Mood and Anxiety Program, National Institute of Mental Health, Bethesda, MD; Dr. Kaufman is with the Department of Psychiatry, Yale University, New Haven, CT; Ms. Hodgdon is with the Department of Psychology, Temple University, Philadelphia; Ms. Masten is with the Department of Psychology, University of California, Los Angeles; and Ms. Jazbec is with the Department of Psychology, University of Zurich, Zurich, Switzerland.
- Hodgdon HB Drs. Guyer, Pine, and Ernst are with the Mood and Anxiety Program, National Institute of Mental Health, Bethesda, MD; Dr. Kaufman is with the Department of Psychiatry, Yale University, New Haven, CT; Ms. Hodgdon is with the Department of Psychology, Temple University, Philadelphia; Ms. Masten is with the Department of Psychology, University of California, Los Angeles; and Ms. Jazbec is with the Department of Psychology, University of Zurich, Zurich, Switzerland.
- Masten CL Drs. Guyer, Pine, and Ernst are with the Mood and Anxiety Program, National Institute of Mental Health, Bethesda, MD; Dr. Kaufman is with the Department of Psychiatry, Yale University, New Haven, CT; Ms. Hodgdon is with the Department of Psychology, Temple University, Philadelphia; Ms. Masten is with the Department of Psychology, University of California, Los Angeles; and Ms. Jazbec is with the Department of Psychology, University of Zurich, Zurich, Switzerland.
- Jazbec S Drs. Guyer, Pine, and Ernst are with the Mood and Anxiety Program, National Institute of Mental Health, Bethesda, MD; Dr. Kaufman is with the Department of Psychiatry, Yale University, New Haven, CT; Ms. Hodgdon is with the Department of Psychology, Temple University, Philadelphia; Ms. Masten is with the Department of Psychology, University of California, Los Angeles; and Ms. Jazbec is with the Department of Psychology, University of Zurich, Zurich, Switzerland.
- Pine DS Drs. Guyer, Pine, and Ernst are with the Mood and Anxiety Program, National Institute of Mental Health, Bethesda, MD; Dr. Kaufman is with the Department of Psychiatry, Yale University, New Haven, CT; Ms. Hodgdon is with the Department of Psychology, Temple University, Philadelphia; Ms. Masten is with the Department of Psychology, University of California, Los Angeles; and Ms. Jazbec is with the Department of Psychology, University of Zurich, Zurich, Switzerland.
- Ernst M Drs. Guyer, Pine, and Ernst are with the Mood and Anxiety Program, National Institute of Mental Health, Bethesda, MD; Dr. Kaufman is with the Department of Psychiatry, Yale University, New Haven, CT; Ms. Hodgdon is with the Department of Psychology, Temple University, Philadelphia; Ms. Masten is with the Department of Psychology, University of California, Los Angeles; and Ms. Jazbec is with the Department of Psychology, University of Zurich, Zurich, Switzerland.
- 2006-08-24
Published in:
- Journal of the American Academy of Child and Adolescent Psychiatry. - 2006
Adolescent
Child
Child Abuse
Child Behavior Disorders
Depressive Disorder
Female
Humans
Male
Motivation
Reward
Stress Disorders, Post-Traumatic
Surveys and Questionnaires
English
OBJECTIVE
To examine in children the influence of maltreatment and associated psychiatric sequelae on behavioral responses to reward stimuli.
METHOD
A computerized two-choice decision-making task involving probabilistic monetary gains was used to probe elemental processes of goal-directed actions. Using different risk contingencies, the authors examined decision-making, expectations of outcomes, and affective responses to rewards in 38 maltreated children and 21 demographically matched controls (8-14 years old).
RESULTS
Maltreated children selected risk options faster than controls; however, whereas controls responded more quickly as the chance of winning increased, maltreated children did not vary in response speed as a function of the likelihood of winning. When choosing between high- and low-risk options, maltreated children with depressive disorders more frequently selected safe over risky choices than did controls. No group differences emerged in self-report ratings of positive or negative reactions to winning or not winning, respectively.
CONCLUSIONS
This initial experimental study of responses to reward lays the groundwork for subsequent research on neurodevelopmental aspects of reward processes in relationship to maltreatment and psychopathology. Clinical applications of these data may be relevant for developing treatment plans for maltreated children, particularly those with depression.
To examine in children the influence of maltreatment and associated psychiatric sequelae on behavioral responses to reward stimuli.
METHOD
A computerized two-choice decision-making task involving probabilistic monetary gains was used to probe elemental processes of goal-directed actions. Using different risk contingencies, the authors examined decision-making, expectations of outcomes, and affective responses to rewards in 38 maltreated children and 21 demographically matched controls (8-14 years old).
RESULTS
Maltreated children selected risk options faster than controls; however, whereas controls responded more quickly as the chance of winning increased, maltreated children did not vary in response speed as a function of the likelihood of winning. When choosing between high- and low-risk options, maltreated children with depressive disorders more frequently selected safe over risky choices than did controls. No group differences emerged in self-report ratings of positive or negative reactions to winning or not winning, respectively.
CONCLUSIONS
This initial experimental study of responses to reward lays the groundwork for subsequent research on neurodevelopmental aspects of reward processes in relationship to maltreatment and psychopathology. Clinical applications of these data may be relevant for developing treatment plans for maltreated children, particularly those with depression.
- Language
-
- English
- Open access status
- closed
- Identifiers
-
- DOI 10.1097/01.chi.0000227882.50404.11
- PMID 16926613
- Persistent URL
- https://sonar.ch/global/documents/280438
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