One-Pot Synthesis of 1-[(Triisopropylsilyl)ethynyl]-1,2-benziodoxol-3(1H)-one (TIPS-EBX): Process Safety Assessment and Impact of Impurities on Product Stability

• Hari, Durga Prasad Laboratory of Catalysis and Organic Synthesis, Ecole Polytechnique Fedérale de Lausanne, EPFL SB ISIC LCSO, BCH 4306, 1015 Lausanne, Switzerland
• Caramenti, Paola Laboratory of Catalysis and Organic Synthesis, Ecole Polytechnique Fedérale de Lausanne, EPFL SB ISIC LCSO, BCH 4306, 1015 Lausanne, Switzerland
• Schouwey, Lionel Laboratory of Catalysis and Organic Synthesis, Ecole Polytechnique Fedérale de Lausanne, EPFL SB ISIC LCSO, BCH 4306, 1015 Lausanne, Switzerland
• Chang, Miyeon Laboratory of Catalysis and Organic Synthesis, Ecole Polytechnique Fedérale de Lausanne, EPFL SB ISIC LCSO, BCH 4306, 1015 Lausanne, Switzerland
• Nicolai, Stefano Laboratory of Catalysis and Organic Synthesis, Ecole Polytechnique Fedérale de Lausanne, EPFL SB ISIC LCSO, BCH 4306, 1015 Lausanne, Switzerland
• Bachert, Donald Chemical Engineering R&D, Merck & Co., Inc., Rahway, New Jersey 07065, United States
• Wright, Timothy Chemical Engineering R&D, Merck & Co., Inc., Rahway, New Jersey 07065, United States
• Orella, Chuck Chemical Engineering R&D, Merck & Co., Inc., Rahway, New Jersey 07065, United States
• Waser, Jerome ORCID Laboratory of Catalysis and Organic Synthesis, Ecole Polytechnique Fedérale de Lausanne, EPFL SB ISIC LCSO, BCH 4306, 1015 Lausanne, Switzerland

Physical and Theoretical Chemistry

Organic Chemistry