Journal article
Revisiting transfusion safety and alternatives to transfusion.
- Schoettker P Lausanne University Hospital CHUV, Department of Anesthesiology, rue du Bugnon 21, 1011 Lausanne, Switzerland. Electronic address: patrick.schoettker@chuv.ch.
- Marcucci CE Lausanne University Hospital CHUV, Department of Anesthesiology, rue du Bugnon 21, 1011 Lausanne, Switzerland.
- Casso G Cardiocentro Ticino, Department of Cardiac Anesthesiology and Intensive Care, Via Tesserete 48, 6900 Lugano, Switzerland.
- Heim C Lausanne University Hospital CHUV, Department of Anesthesiology, rue du Bugnon 21, 1011 Lausanne, Switzerland.
- 2016-08-01
Published in:
- Presse medicale (Paris, France : 1983). - 2016
English
Transfusion of blood products can be life saving when used appropriately. It carries however at the same time a potential for morbidity and mortality, depending on the patient, the product or the setting. Numerous strategies have been elaborated to minimize these risks, and in recent years, transfusion has no longer been regarded as essential for the management of a wide range of diseases. Uncomplicated surgeries in well-prepared patients can now be conducted without the use of transfusions. Questions about transfusion safety and shortage have led to extensive research on alternatives to blood transfusion, ranging from non-pharmacological to pharmacological solutions. Restrictive transfusion therapies, preoperative autologous blood donations, perioperative red cell salvage, acute normovolaemic haemodilution techniques or patient blood management are potential solutions where prothrombin complex or fibrinogen concentrates, synthetic anti-fibrinolytic agents, desmopressin, rFVIIa, or erythropoiesis stimulating agents may play a complementary pharmacologic role.
- Language
-
- English
- Open access status
- closed
- Identifiers
-
- DOI 10.1016/j.lpm.2016.06.023
- PMID 27476018
- Persistent URL
- https://sonar.ch/global/documents/283408
Statistics
Document views: 20
File downloads: