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Cap-and-tag solid phase oligosaccharide synthesis.
Journal article

Cap-and-tag solid phase oligosaccharide synthesis.

  • Carrel FR Laboratory of Organic Chemistry, Swiss Federal Institute of Technology (ETH) Zürich, Wolfgang-Pauli-Strasse 10, 8093 Zürich, Switzerland.
  • Seeberger PH
  • 2007-10-25
Published in:
  • The Journal of organic chemistry. - 2008
Acetylation
Carbohydrate Sequence
Glucose
Glycosides
Glycosylation
Mannose
Molecular Sequence Data
Oligosaccharides
English A new "cap-and-tag" strategy is applied to solid phase oligosaccharide synthesis. Acetyl-capping and fluorous-tagging allowed for the facile separation of the desired F-tagged oligosaccharide from the acetyl-capped deletion sequences using fluorous solid phase extraction. To illustrate this approach, a protected Glc-beta-(1-->6)-Man-alpha-(1-->6)-Glc-beta-1-->pentenyl trisaccharide was synthesized.
Language
  • English
Open access status
closed
Identifiers
Persistent URL
https://sonar.ch/global/documents/284757
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