Journal article
Parameters affecting microwave-assisted extraction of withanolides.
- Kaufmann B University of Geneva, Laboratory of Pharmaceutical Analytical Chemistry, 20 bd d'Yvoy, CH-1211 Geneva 4, Switzerland.
- Christen P
- Veuthey JL
- 2001-11-14
Published in:
- Phytochemical analysis : PCA. - 2001
English
Focused microwave-assisted extraction was applied to the extraction of three main withanolides from airdried leaves of Iochroma gesnerioides, namely, withaferin A, iochromolide and withacnistin. Six extraction variables, i.e. nature and volume of extracting solvent, sample moisture, extraction time, power of irradiation and particle size, were investigated with respect to the recovery of withanolides. The most favourable conditions were obtained by using powdered plant material (< 220 microns), previously impregnated with water for 15 min, and extracted with methanol for 40 s at 25 W. The results obtained using the optimised method were compared to those achievable with Soxhlet extraction.
- Language
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- English
- Open access status
- closed
- Identifiers
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- DOI 10.1002/pca.599
- PMID 11705260
- Persistent URL
- https://sonar.ch/global/documents/285232
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