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[Bilateral deafness due to labyrinthitis in a patient with Crohn's disease].

  • Weisert JU Klinik für Hals-, Nasen-, Ohrenheilkunde, Hals- und Gesichtschirurgie, Universitätsspital Zürich, Frauenklinikstr 24, 8091 Zürich, Schweiz. jan.weisert@usz.ch
  • Veraguth D
  • Probst R
  • 2011-07-07
Published in:
  • HNO. - 2012
Adult
Audiometry, Pure-Tone
Cochlear Implantation
Crohn Disease
Deafness
Disease Progression
Functional Laterality
Humans
Labyrinthitis
Magnetic Resonance Imaging
Male
Postural Balance
Tinnitus
Vestibular Evoked Myogenic Potentials
English Labyrinthitis with vestibulocochlear dysfunction in chronic inflammatory bowl disease is a rare but well described manifestation or complication. The diagnostic and therapeutic possibilities and limitations of this inflammatory otopathy are presented and discussed in the context of a case report. A bilateral loss of vestibular function and sensorineural hearing loss occurred in a 26-year-old male patient with previously diagnosed Crohn's disease. He was treated with immune suppressive therapy during the onset and development of cochleovestibular symptoms. Diagnostic tests included pure tone audiograms, speech audiometry, caloric tests, VEMPs, and MRI. Therapy included azathioprine, corticosteroids (systemic and intratympanic), monoclonal antibodies, and cochlear implants. Despite immunosuppressive therapy including monoclonal antibodies, the patient progressively lost his hearing. Finally, bilateral cochlear implantation was carried out with good results. The treatment of patients with systemic inflammatory or autoimmune disease affecting the cochlear-vestibular organ is challenging. An interdisciplinary approach is needed. In cases of bilateral deafness, cochlear implantation is a satisfactory treatment and should not be delayed unnecessarily.
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  • English
Open access status
green
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Persistent URL
https://sonar.ch/global/documents/287022
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