Mitochondrial Homeostasis: How Do Dimers of Mitofusins Mediate Mitochondrial Fusion?
- Daumke O Max-Delbrück Centrum für Molekulare Medizin, Crystallography Robert-Rössle-Strasse 10, 13125 Berlin, Germany; Freie Universität Berlin, Institute of Chemistry and Biochemistry, Takustraße 6, 14195 Berlin, Germany. Electronic address: oliver.daumke@mdc-berlin.de.
- Roux A University of Geneva, Department of Biochemistry, 30 quai Ernest Ansermet, CH-1211 Geneva 4, Switzerland; Swiss National Centre for Competence in Research Programme Chemical Biology, CH-1211 Geneva, Switzerland. Electronic address: aurelien.roux@unige.ch.
- 2017-05-10
Published in:
- Current biology : CB. - 2017
Homeostasis
Membrane Fusion
Mitochondria
Mitochondrial Dynamics
Mitochondrial Membrane Transport Proteins
Mitochondrial Membranes
Protein Multimerization
English
Mitochondria have high fusion and fission rates to maintain their size and number throughout the cell cycle. How is fusion mediated? New structural studies propose mechanisms by which the dynamin-like mitofusin proteins promote fusion of mitochondria.
- Language
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- English
- Open access status
- bronze
- Identifiers
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- DOI 10.1016/j.cub.2017.03.024
- PMID 28486121
- Persistent URL
- https://sonar.ch/global/documents/29218
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