Physical activity intensity, bout-duration, and cardiometabolic risk markers in children and adolescents.
- Tarp J Research Unit for Exercise Epidemiology, Department of Sports Science and Clinical Biomechanics, Centre of Research in Childhood Health, University of Southern Denmark, Odense, Denmark. jakob.tarp@nih.no.
- Child A University of Cambridge, Cambridge, UK.
- White T Medical Research Council Epidemiology Unit, University of Cambridge, Cambridge, UK.
- Westgate K Medical Research Council Epidemiology Unit, University of Cambridge, Cambridge, UK.
- Bugge A Research Unit for Exercise Epidemiology, Department of Sports Science and Clinical Biomechanics, Centre of Research in Childhood Health, University of Southern Denmark, Odense, Denmark.
- Grøntved A Research Unit for Exercise Epidemiology, Department of Sports Science and Clinical Biomechanics, Centre of Research in Childhood Health, University of Southern Denmark, Odense, Denmark.
- Wedderkopp N Research Unit for Exercise Epidemiology, Department of Sports Science and Clinical Biomechanics, Centre of Research in Childhood Health, University of Southern Denmark, Odense, Denmark.
- Andersen LB Department of Teacher Education and Sport, Western Norwegian University of Applied Sciences, Sogndal, Norway.
- Cardon G Department of Movement and Sports Sciences, Ghent University, 9000, Ghent, Belgium.
- Davey R Centre for Research and Action in Public Health, University of Canberra, Canberra, Australia.
- Janz KF Department of Health and Human Physiology, University of Iowa, Iowa City, USA.
- Kriemler S Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland.
- Northstone K Bristol Medical School, University of Bristol, Bristol, UK.
- Page AS Centre for Exercise, Nutrition and Health Sciences, School for Policy Studies, University of Bristol, Bristol, UK.
- Puder JJ Service of Endocrinology, Diabetes and Metabolism and Division of Pediatric Endocrinology, Diabetes and Obesity, University Hospital Lausanne, Lausanne, Switzerland.
- Reilly JJ University of Strathclyde, Physical Activity for Health Group, School of Psychological Sciences and Health, Glasgow, Scotland, UK.
- Sardinha LB Exercise and Health Laboratory, Faculty of Human Kinetics, Universidade de Lisboa, Lisbon, Portugal.
- van Sluijs EMF Medical Research Council Epidemiology Unit, University of Cambridge, Cambridge, UK.
- Ekelund U Department of Sports Medicine, Norwegian School of Sport Sciences, Oslo, Norway.
- Wijndaele K Medical Research Council Epidemiology Unit, University of Cambridge, Cambridge, UK.
- Brage S Medical Research Council Epidemiology Unit, University of Cambridge, Cambridge, UK.
- 2018-07-15
Published in:
- International journal of obesity (2005). - 2018
Adolescent
Biomarkers
Blood Glucose
Blood Pressure
Body Mass Index
Cardiovascular Diseases
Child
Child, Preschool
Cross-Sectional Studies
Exercise
Humans
Insulin
Obesity
Physical Conditioning, Human
Risk Factors
Waist Circumference
English
OBJECTIVES
To determine the role of physical activity intensity and bout-duration in modulating associations between physical activity and cardiometabolic risk markers.
METHODS
A cross-sectional study using the International Children's Accelerometry Database (ICAD) including 38,306 observations (in 29,734 individuals aged 4-18 years). Accelerometry data was summarized as time accumulated in 16 combinations of intensity thresholds (≥500 to ≥3000 counts/min) and bout-durations (≥1 to ≥10 min). Outcomes were body mass index (BMI, kg/m2), waist circumference, biochemical markers, blood pressure, and a composite score of these metabolic markers. A second composite score excluded the adiposity component. Linear mixed models were applied to elucidate the associations and expressed per 10 min difference in daily activity above the intensity/bout-duration combination. Estimates (and variance) from each of the 16 combinations of intensity and bout-duration examined in the linear mixed models were analyzed in meta-regression to investigate trends in the association.
RESULTS
Each 10 min positive difference in physical activity was significantly and inversely associated with the risk factors irrespective of the combination of intensity and bout-duration. In meta-regression, each 1000 counts/min increase in intensity threshold was associated with a -0.027 (95% CI: -0.039 to -0.014) standard deviations lower composite risk score, and a -0.064 (95% CI: -0.09 to -0.038) kg/m2 lower BMI. Conversely, meta-regression suggested bout-duration was not significantly associated with effect-sizes (per 1 min increase in bout-duration: -0.002 (95% CI: -0.005 to 0.0005) standard deviations for the composite risk score, and -0.005 (95% CI: -0.012 to 0.002) kg/m2 for BMI).
CONCLUSIONS
Time spent at higher intensity physical activity was the main determinant of variation in cardiometabolic risk factors, not bout-duration. Greater magnitude of associations was consistently observed with higher intensities. These results suggest that, in children and adolescents, physical activity, preferably at higher intensities, of any bout-duration should be promoted.
To determine the role of physical activity intensity and bout-duration in modulating associations between physical activity and cardiometabolic risk markers.
METHODS
A cross-sectional study using the International Children's Accelerometry Database (ICAD) including 38,306 observations (in 29,734 individuals aged 4-18 years). Accelerometry data was summarized as time accumulated in 16 combinations of intensity thresholds (≥500 to ≥3000 counts/min) and bout-durations (≥1 to ≥10 min). Outcomes were body mass index (BMI, kg/m2), waist circumference, biochemical markers, blood pressure, and a composite score of these metabolic markers. A second composite score excluded the adiposity component. Linear mixed models were applied to elucidate the associations and expressed per 10 min difference in daily activity above the intensity/bout-duration combination. Estimates (and variance) from each of the 16 combinations of intensity and bout-duration examined in the linear mixed models were analyzed in meta-regression to investigate trends in the association.
RESULTS
Each 10 min positive difference in physical activity was significantly and inversely associated with the risk factors irrespective of the combination of intensity and bout-duration. In meta-regression, each 1000 counts/min increase in intensity threshold was associated with a -0.027 (95% CI: -0.039 to -0.014) standard deviations lower composite risk score, and a -0.064 (95% CI: -0.09 to -0.038) kg/m2 lower BMI. Conversely, meta-regression suggested bout-duration was not significantly associated with effect-sizes (per 1 min increase in bout-duration: -0.002 (95% CI: -0.005 to 0.0005) standard deviations for the composite risk score, and -0.005 (95% CI: -0.012 to 0.002) kg/m2 for BMI).
CONCLUSIONS
Time spent at higher intensity physical activity was the main determinant of variation in cardiometabolic risk factors, not bout-duration. Greater magnitude of associations was consistently observed with higher intensities. These results suggest that, in children and adolescents, physical activity, preferably at higher intensities, of any bout-duration should be promoted.
- Language
-
- English
- Open access status
- hybrid
- Identifiers
-
- DOI 10.1038/s41366-018-0152-8
- PMID 30006582
- Persistent URL
- https://sonar.ch/global/documents/297409
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