Bilateral Spontaneous Regression of Vestibular Schwannoma in Neurofibromatosis Type 2.
- Sebök M Department of Neurosurgery, University Hospital Zurich, University of Zurich, Zurich, Switzerland; Clinical Neuroscience Center, University Hospital Zurich, Zurich, Switzerland. Electronic address: martina.seboek@usz.ch.
- van Niftrik CHB Department of Neurosurgery, University Hospital Zurich, University of Zurich, Zurich, Switzerland; Clinical Neuroscience Center, University Hospital Zurich, Zurich, Switzerland.
- Bozinov O Department of Neurosurgery, University Hospital Zurich, University of Zurich, Zurich, Switzerland; Clinical Neuroscience Center, University Hospital Zurich, Zurich, Switzerland.
- 2018-02-25
Published in:
- World neurosurgery. - 2018
Conservative management
Magnetic resonance imaging
Neurofibromatosis type 2
Spontaneous regression
Tumor volume
Vestibular schwannoma
“Watch and wait”
Follow-Up Studies
Humans
Male
Middle Aged
Neurofibromatosis 2
Neuroma, Acoustic
Remission, Spontaneous
Watchful Waiting
English
BACKGROUND
Patients with neurofibromatosis type 2 and bilateral vestibular schwannoma (VS) are frequently treated surgically for any tumor progression, and often repeated surgery or radiation treatment is even considered. Some VS progression occurs without the development of new clinical symptoms, or it does not progress in size over many years, even in the absence of any specific treatment.
CASE DESCRIPTION
A 61-year-old male patient with neurofibromatosis type 2 presented with bilateral VS. In a long-term follow-up, both had increased in size but also showed bilateral spontaneous regression during an 11-year follow-up period with a "watch-and-wait" strategy.
CONCLUSIONS
We emphasize conservative treatment ("watch and wait") in older patients even with long-term tumor progression without significant compression-related clinical symptoms.
Patients with neurofibromatosis type 2 and bilateral vestibular schwannoma (VS) are frequently treated surgically for any tumor progression, and often repeated surgery or radiation treatment is even considered. Some VS progression occurs without the development of new clinical symptoms, or it does not progress in size over many years, even in the absence of any specific treatment.
CASE DESCRIPTION
A 61-year-old male patient with neurofibromatosis type 2 presented with bilateral VS. In a long-term follow-up, both had increased in size but also showed bilateral spontaneous regression during an 11-year follow-up period with a "watch-and-wait" strategy.
CONCLUSIONS
We emphasize conservative treatment ("watch and wait") in older patients even with long-term tumor progression without significant compression-related clinical symptoms.
- Language
-
- English
- Open access status
- green
- Identifiers
-
- DOI 10.1016/j.wneu.2018.02.075
- PMID 29477000
- Persistent URL
- https://sonar.ch/global/documents/30269
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