Journal article
Adventures of a pore-forming toxin at the target cell surface.
- Abrami L Dept of Biochemistry, University of Geneva, 30 quai E. Ansermet, 1211 Geneva 4, Switzerland.
- Fivaz M
- van der Goot FG
- 2001-02-07
Published in:
- Trends in microbiology. - 2000
Aeromonas hydrophila
Animals
Bacterial Toxins
Biopolymers
Cell Membrane
Cell Membrane Permeability
Humans
Pore Forming Cytotoxic Proteins
Receptors, Cell Surface
English
The past three years have shed light on how the pore-forming toxin aerolysin binds to its target cell and then hijacks cellular devices to promote its own polymerization and pore formation. This selective permeabilization of the plasma membrane has unexpected intracellular consequences that might explain the importance of aerolysin in Aeromonas pathogenicity.
- Language
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- English
- Open access status
- closed
- Identifiers
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- DOI 10.1016/s0966-842x(00)01722-4
- PMID 10754575
- Persistent URL
- https://sonar.ch/global/documents/33141
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