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Overview of the centriole architecture.
Journal article

Overview of the centriole architecture.

  • LeGuennec M University of Geneva, Department of Cell Biology, Sciences III, Geneva, Switzerland.
  • Klena N University of Geneva, Department of Cell Biology, Sciences III, Geneva, Switzerland.
  • Aeschlimann G Ribosome Studio Aeschlimann, Einsiedlerstrasse 6, Oberrieden, 8942, Switzerland.
  • Hamel V University of Geneva, Department of Cell Biology, Sciences III, Geneva, Switzerland. Electronic address: virginie.hamel@unige.ch.
  • Guichard P University of Geneva, Department of Cell Biology, Sciences III, Geneva, Switzerland. Electronic address: paul.guichard@unige.ch.
  • 2020-11-11
Published in:
  • Current opinion in structural biology. - 2020
Molecular Biology
Structural Biology
English The centriole is a magnificent molecular assembly of several giga-daltons, one of the largest of the eukaryotic cell, and whose atomic structure remains unsolved to date. However, numerous electron microscopy, cryo-tomography, and super-resolution studies now make it possible to establish a global architectural view of it with its different sub-regions. These analyses broaden our understanding by providing additional informations to cell biology and structural biology approaches. In this review, we describe current knowledge on the overall organization of the centriole. We will highlight each sub-structural element, their differences between species and their putative protein composition. We will conclude on the current limitations that still take us away from a complete atomic view of the centriole architecture.
Language
  • English
Open access status
hybrid
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Persistent URL
https://sonar.ch/global/documents/34455
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