Telomerase unplugged.
- Cristofari G Swiss Institute for Experimental Cancer Research, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
- Sikora K
- Lingner J
- 2007-03-22
Published in:
- ACS chemical biology. - 2007
English
The control of telomerase activity at chromosome ends by telomere-binding proteins is critical for telomere length homeostasis. Two recent papers identify TPP1 as a critical mediator of this control. TPP1 forms part of the telomeric shelterin complex while also associating with telomerase, stimulating its activity and processivity.
- Language
-
- English
- Open access status
- bronze
- Identifiers
-
- DOI 10.1021/cb700037c
- PMID 17373762
- Persistent URL
- https://sonar.ch/global/documents/37947
Statistics
Document views: 61
File downloads:
- Full-text: 0