Back
Inflammation: IL-36 has proinflammatory effects in skin but not in joints.
Journal article

Inflammation: IL-36 has proinflammatory effects in skin but not in joints.

  • Dietrich D Division of Rheumatology, University Hospitals of Geneva, 26 Avenue de Beau-Séjour, 1211 Geneva 14, Switzerland.
  • Gabay C Division of Rheumatology, University Hospitals of Geneva, 26 Avenue de Beau-Séjour, 1211 Geneva 14, Switzerland.
  • 2014-09-10
Published in:
  • Nature reviews. Rheumatology. - 2014
Animals
Arthritis
Arthritis, Experimental
Dermatitis
Humans
Inflammation
Interleukin-1
Mice
Psoriasis
Receptors, Interleukin
Receptors, Interleukin-1
Skin
Synovial Membrane
Synovitis
English Given the known involvement of IL-36 in psoriasis it might be surprising that the latest mouse models show that inhibiting IL-36 signalling does not alter the course of inflammatory arthritis. Can we now add IL-36 to the list of inflammatory mediators that are not viable DMARD targets?
Language
  • English
Open access status
closed
Identifiers
Persistent URL
https://sonar.ch/global/documents/38940
Statistics
Document views: 26 File downloads: