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Common principles of protein translocation across membranes.
Journal article

Common principles of protein translocation across membranes.

  • 1996-03-15
Published in:
  • Science (New York, N.Y.). - 1996
Amino Acid Sequence
Bacteria
Biological Transport
Cell Membrane
Chloroplasts
Cytosol
Endoplasmic Reticulum
GTP Phosphohydrolases
Intracellular Membranes
Membrane Proteins
Microbodies
Mitochondria
Molecular Chaperones
Molecular Sequence Data
Protein Folding
Protein Sorting Signals
Proteins
English Most major systems that transport proteins across a membrane share the following features: an amino-terminal transient signal sequence on the transported protein, a targeting system on the cis side of the membrane, a hetero-oligomeric transmembrane channel that is gated both across and within the plane of the membrane, a peripherally attached protein translocation motor that is powered by the hydrolysis of nucleoside triphosphate, and a protein folding system on the trans side of the membrane. These transport systems are divided into two families: export systems that export proteins out of the cytosol, and import systems that transport proteins into cytosol-like compartments.
Language
  • English
Open access status
closed
Identifiers
Persistent URL
https://sonar.ch/global/documents/45442
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