[Severe H1N1 2009 influenza infection in adults: the French experience].
- Mercat A 1Département de réanimation médicale et médecine hyperbare, CHU d'Angers, 4, rue Larrey, F-49933 Angers cedex 09, France.
- Pham T 2Service de réanimation médicale, hôpital Henri-Mondor, Assistance publique-Hôpitaux de Paris, université Paris-Est, Créteil, France.
- Rozé H 3Département d'anesthésie-réanimation 2, CHU de Bordeaux, Pessac, France.
- Cuquemelle E 2Service de réanimation médicale, hôpital Henri-Mondor, Assistance publique-Hôpitaux de Paris, université Paris-Est, Créteil, France.
- Brun-Buisson C 2Service de réanimation médicale, hôpital Henri-Mondor, Assistance publique-Hôpitaux de Paris, université Paris-Est, Créteil, France.
- Brochard L 4Département de soins intensifs, hôpital cantonal universitaire de Genève, université de Genève, Genève, Suisse.
- Richard JC 6Service de réanimation médicale, CHU Charles-Nicolle et UPRES-EA 3830, université de Rouen, Rouen, France.
- 2020-04-15
Published in:
- Reanimation : journal de la Societe de reanimation de langue francaise. - 2011
Acute respiratory distress syndrome
Corticosteroids
Flu
H1N1
Intensive care
Mechanical ventilation
Pandemic
Pneumonia
English
The REVA-Flu-SRLF register allowed collection of data from 562 patients infected with H1N1 influenza virus 2009 and hospitalized in the intensive care unit (ICU). The overall mortality of these patients was 20%. The use of invasive ventilation, heart failure, and immunosuppression were associated with mortality. Three hundred forty-one (82%) among the 417 mechanically ventilated patients had an acute respiratory distress syndrome (ARDS). One hundred sixty-nine (30%) had a bacterial co-infection. Corticosteroid therapy was associated with an increased mortality in patients with ARDS. The occupancy rate associated with influenza patients crossed the threshold of 15% in many ICUs.
- Language
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- English
- Open access status
- green
- Identifiers
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- DOI 10.1007/s13546-011-0266-7
- PMID 32288724
- Persistent URL
- https://sonar.ch/global/documents/46764
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