Back
First-person body view modulates the neural substrates of episodic memory and autonoetic consciousness: A functional connectivity study.
Journal article

First-person body view modulates the neural substrates of episodic memory and autonoetic consciousness: A functional connectivity study.

  • Gauthier B Laboratory of Cognitive Neuroscience, Center for Neuroprosthetics and Brain Mind Institute, Swiss Federal Institute of Technology (EPFL), Chemin des Mines 9, 1202 Geneva, Switzerland; Center for Neuroprosthetics, Swiss Federal Institute of Technology (EPFL), Campus Biotech, Geneva, Switzerland. Electronic address: baptiste.gauthier@epfl.ch.
  • Bréchet L Berenson-Allen Center for Noninvasive Brain Stimulation, Department of neurology, Beth Israel Deaconess Medical Center, 02215 Boston, MA, USA; Hinda and Arthur Marcus Institute for Aging Research, 02131 Boston, MA, USA; Center for Biomedical Imaging (CIBM), Lausanne, Geneva, Switzerland; Department of Neurology, University of Geneva, 24 Rue Micheli-du-Crest, 1211 Geneva, Switzerland.
  • Lance F Laboratory of Cognitive Neuroscience, Center for Neuroprosthetics and Brain Mind Institute, Swiss Federal Institute of Technology (EPFL), Chemin des Mines 9, 1202 Geneva, Switzerland; Center for Neuroprosthetics, Swiss Federal Institute of Technology (EPFL), Campus Biotech, Geneva, Switzerland.
  • Mange R Laboratory of Cognitive Neuroscience, Center for Neuroprosthetics and Brain Mind Institute, Swiss Federal Institute of Technology (EPFL), Chemin des Mines 9, 1202 Geneva, Switzerland; Imverse SA, Chemin du Pré-Fleuri 3, 1228 Geneva, Switzerland.
  • Herbelin B Laboratory of Cognitive Neuroscience, Center for Neuroprosthetics and Brain Mind Institute, Swiss Federal Institute of Technology (EPFL), Chemin des Mines 9, 1202 Geneva, Switzerland; Center for Neuroprosthetics, Swiss Federal Institute of Technology (EPFL), Campus Biotech, Geneva, Switzerland.
  • Faivre N Laboratoire de Psychologie et Neurocognition CNRS UMR 5105 UGA BSHM, France.
  • Bolton TAW Department of Radiology and Medical Informatics, CIBM, University of Geneva, Geneva, Switzerland; Institute of Bioengineering, Swiss Federal Institute of Technology (EPFL), Campus Biotech, Chemin des Mines 10, 1202, Geneva, Switzerland; Department of Decoded Neurofeedback, ATR Computational Neuroscience Laboratories, 2-2-2 Hikaridai, Seika-cho, Soraku-gun, Kyoto 619-0288, Japan.
  • Ville DV Department of Radiology and Medical Informatics, CIBM, University of Geneva, Geneva, Switzerland; Institute of Bioengineering, Swiss Federal Institute of Technology (EPFL), Campus Biotech, Chemin des Mines 10, 1202, Geneva, Switzerland.
  • Blanke O Laboratory of Cognitive Neuroscience, Center for Neuroprosthetics and Brain Mind Institute, Swiss Federal Institute of Technology (EPFL), Chemin des Mines 9, 1202 Geneva, Switzerland; Center for Neuroprosthetics, Swiss Federal Institute of Technology (EPFL), Campus Biotech, Geneva, Switzerland; Department of Neurology, University of Geneva, 24 Rue Micheli-du-Crest, 1211 Geneva, Switzerland.
Show more…
  • 2020-09-15
Published in:
  • NeuroImage. - 2020
Autonoetic consciousness
Bodily self-consciousness
Episodic memory
Resting-state functional connectivity
Virtual reality
English Episodic memory (EM) is classically conceived as a memory for events, localized in space and time, and characterized by autonoetic consciousness (ANC) allowing to mentally travel back in time and subjectively relive an event. Building on recent evidence that the first-person visual co-perception of one's own body during encoding impacts EM, we used a scene recognition task in immersive virtual reality (VR) and measured how first-person body view would modulate peri-encoding resting-state fMRI, EM performance, and ANC. Specifically, we investigated the impact of body view on post-encoding functional connectivity in an a priori network of regions related either to EM or multisensory bodily processing and used these regions in a seed-to-whole brain analysis. Post-encoding connectivity between right hippocampus (rHC) and right parahippocampus (rPHC) was enhanced when participants encoded scenes while seeing their body. Moreover, the strength of connectivity between the rHC, rPHC and the neocortex displayed two main patterns with respect to body view. The connectivity with a sensorimotor fronto-parietal network, comprising primary somatosensory and primary motor cortices, correlated with ANC after - but not before - encoding, depending on body view. The opposite change of connectivity was found between rHC, rPHC and the medial parietal cortex (from being correlated with ANC before encoding to an absence of correlation after encoding), but irrespective of body view. Linking immersive VR and fMRI for the study of EM and ANC, these findings suggest that seeing one's own body during encoding impacts the brain activity related to EM formation by modulating the connectivity between the right hippocampal formation and the neocortical regions involved in the processing of multisensory bodily signals and self-consciousness.
Language
  • English
Open access status
gold
Identifiers
Persistent URL
https://sonar.ch/global/documents/46898
Statistics
Document views: 42 File downloads: