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Multilabeled 13C substrates as probes in in vivo 13C and 1H NMR spectroscopy.
Journal article

Multilabeled 13C substrates as probes in in vivo 13C and 1H NMR spectroscopy.

  • 1989-12-01
Published in:
  • NMR in biomedicine. - 1989
Animals
Brain
Liver
Magnetic Resonance Spectroscopy
Rats
Rats, Inbred Strains
English The potential use of 13C multilabeled substrates has been studied in biological applications using in vivo and in vitro proton and 13C NMR spectroscopy. In 13C NMR spectroscopy, multilabeled compounds allow the simultaneous observation of several nuclei or increase distinctly the signal to noise ratio due to a higher degree of enrichment. Contiguous labeling of substrates leads to homonuclear 13C-13C spin couplings and provides a simple means to distinguish between endogenous stores of metabolites and metabolites derived from added substrates.
Language
  • English
Open access status
closed
Identifiers
Persistent URL
https://sonar.ch/global/documents/47058
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