Journal article
Positron emission tomography/computed tomography in patients with hepatocellular carcinoma undergoing liver transplantation. Useful, necessary or irrelevant?
- Cascales-Campos PA Department of Surgery, Liver Transplantation Unit, Hospital Clínico Universitario Virgen de la Arrixaca, IMIB-Arrixaca, Murcia, Spain.
- Romero PR Department of Surgery, Liver Transplantation Unit, Hospital Clínico Universitario Virgen de la Arrixaca, IMIB-Arrixaca, Murcia, Spain.
- Schneider MA Department of Surgery and Transplantation, University Hospital of Zurich, Zurich, Switzerland.
- Lopez-Lopez V Department of Surgery, Liver Transplantation Unit, Hospital Clínico Universitario Virgen de la Arrixaca, IMIB-Arrixaca, Murcia, Spain. Electronic address: victorrelopez@gmail.com.
- Navarro JL Department of Nuclear Medicine, Hospital Clínico Universitario Virgen de la Arrixaca, IMIB-Arrixaca, Murcia, Spain.
- Frutos L Department of Nuclear Medicine, Hospital Clínico Universitario Virgen de la Arrixaca, IMIB-Arrixaca, Murcia, Spain.
- Pons Miñano JA Department of Hepatology, Liver Transplantation Unit Hospital Clínico Universitario Virgen de la Arrixaca, IMIB-Arrixaca, Murcia, Spain.
- Paricio PP Department of Surgery, Liver Transplantation Unit, Hospital Clínico Universitario Virgen de la Arrixaca, IMIB-Arrixaca, Murcia, Spain.
- 2017-06-21
Published in:
- European journal of radiology. - 2017
Hepatocellular carcinoma
Orthotopic liver transplantation
PET
Carcinoma, Hepatocellular
Humans
Liver Cirrhosis
Liver Neoplasms
Liver Transplantation
Multimodal Imaging
Positron Emission Tomography Computed Tomography
Prognosis
English
Hepatocellular Carcinoma (HCC) is an aggressive tumor entity, with the only curative options being surgical resection or orthotopic liver transplantation (OLT). The presence of one single tumor nodule of less than 5 centimeters diameter or a maximum of 3 nodules, with the largest of these not exceeding 3 centimeters (Milan criteria) constitute the clinical situation in which the best results for OLT in patients with HCC have been achieved. The survival of patients fulfilling the Milan criteria after transplantation is comparable to patients with similar tumor stages without cirrhosis, undergoing hepatic resection. The application of PET in oncology has become increasingly common in the last decade as it is a non-invasive tool that also gathers information about the degree of the biological aggressiveness of the tumor. The objective of this study was to perform a review of the literature, identifying the strengths and weaknesses of the PET as a prognostic tool in patients with HCC after OLT.
- Language
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- English
- Open access status
- closed
- Identifiers
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- DOI 10.1016/j.ejrad.2017.03.013
- PMID 28629563
- Persistent URL
- https://sonar.ch/global/documents/47608
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