Journal article

Lucilia cuprina genome unlocks parasitic fly biology to underpin future interventions.

  • Anstead CA Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Victoria 3010, Australia.
  • Korhonen PK Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Victoria 3010, Australia.
  • Young ND Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Victoria 3010, Australia.
  • Hall RS Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Victoria 3010, Australia.
  • Jex AR Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Victoria 3010, Australia.
  • Murali SC Department of Human and Molecular Genetics, Baylor College of Medicine, Houston, Texas 77030, USA.
  • Hughes DS Department of Human and Molecular Genetics, Baylor College of Medicine, Houston, Texas 77030, USA.
  • Lee SF School of Biosciences, The University of Melbourne, Parkville, Victoria 3010, Australia.
  • Perry T School of Biosciences, The University of Melbourne, Parkville, Victoria 3010, Australia.
  • Stroehlein AJ Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Victoria 3010, Australia.
  • Ansell BR Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Victoria 3010, Australia.
  • Breugelmans B Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Victoria 3010, Australia.
  • Hofmann A Structural Chemistry Program, Eskitis Institute for Drug Discovery, Griffith University, Brisbane, Queensland 4111, Australia.
  • Qu J Department of Human and Molecular Genetics, Baylor College of Medicine, Houston, Texas 77030, USA.
  • Dugan S Department of Human and Molecular Genetics, Baylor College of Medicine, Houston, Texas 77030, USA.
  • Lee SL Department of Human and Molecular Genetics, Baylor College of Medicine, Houston, Texas 77030, USA.
  • Chao H Department of Human and Molecular Genetics, Baylor College of Medicine, Houston, Texas 77030, USA.
  • Dinh H Department of Human and Molecular Genetics, Baylor College of Medicine, Houston, Texas 77030, USA.
  • Han Y Department of Human and Molecular Genetics, Baylor College of Medicine, Houston, Texas 77030, USA.
  • Doddapaneni HV Department of Human and Molecular Genetics, Baylor College of Medicine, Houston, Texas 77030, USA.
  • Worley KC Department of Human and Molecular Genetics, Baylor College of Medicine, Houston, Texas 77030, USA.
  • Muzny DM Department of Human and Molecular Genetics, Baylor College of Medicine, Houston, Texas 77030, USA.
  • Ioannidis P Department of Genetic Medicine and Development, University of Geneva &Swiss Institute of Bioinformatics, CH-1211 Geneva, Switzerland.
  • Waterhouse RM Department of Genetic Medicine and Development, University of Geneva &Swiss Institute of Bioinformatics, CH-1211 Geneva, Switzerland.
  • Zdobnov EM Department of Genetic Medicine and Development, University of Geneva &Swiss Institute of Bioinformatics, CH-1211 Geneva, Switzerland.
  • James PJ Ecosciences Precinct, Queensland Alliance for Agriculture and Food Innovation (QAAFI), Queensland Bioscience Precinct, The University of Queensland, St Lucia, Brisbane, Queensland 4072, Australia.
  • Bagnall NH CSIRO Agriculture Flagship, Queensland Bioscience Precinct, St Lucia, Brisbane, Queensland 4067, Australia.
  • Kotze AC CSIRO Agriculture Flagship, Queensland Bioscience Precinct, St Lucia, Brisbane, Queensland 4067, Australia.
  • Gibbs RA Department of Human and Molecular Genetics, Baylor College of Medicine, Houston, Texas 77030, USA.
  • Richards S Department of Human and Molecular Genetics, Baylor College of Medicine, Houston, Texas 77030, USA.
  • Batterham P School of Biosciences, The University of Melbourne, Parkville, Victoria 3010, Australia.
  • Gasser RB Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Victoria 3010, Australia.
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  • 2015-06-26
Published in:
  • Nature communications. - 2015
English Lucilia cuprina is a parasitic fly of major economic importance worldwide. Larvae of this fly invade their animal host, feed on tissues and excretions and progressively cause severe skin disease (myiasis). Here we report the sequence and annotation of the 458-megabase draft genome of Lucilia cuprina. Analyses of this genome and the 14,544 predicted protein-encoding genes provide unique insights into the fly's molecular biology, interactions with the host animal and insecticide resistance. These insights have broad implications for designing new methods for the prevention and control of myiasis.
Language
  • English
Open access status
gold
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Persistent URL
https://sonar.ch/global/documents/50291
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