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Radiographic measurement of alveolar bone loss in the living rat.
Journal article

Radiographic measurement of alveolar bone loss in the living rat.

  • Reymond F Division of Oral Physiopathology and Periodontology, Dental School, Medical Faculty, University of Geneva, Switzerland.
  • Cimasoni G
  • 1997-02-01
Published in:
  • Journal of periodontology. - 1997
Alveolar Bone Loss
Animals
Female
Periodontitis
Radiography
Rats
Rats, Sprague-Dawley
Rats, Wistar
Reproducibility of Results
English We describe a method which allows longitudinal measurements of alveolar bone loss in the living rat. The anesthetized animal is kept in a fixed and reproducible position and radiographs of an upper molar arch are taken with a mammography. In a preliminary study, 4 rats were repeatedly radiographed. In the main study, 10 rats were radiographed at day 0 and after 63 days of diet known to cause periodontitis. The radiographs were enlarged and the amount of bone lost calculated by comparing the weights of the interdental areas reproduced on standard paper. In the preliminary study, the coefficient of variation (C.V.) of the average weights of paper were fairly low (4 to 9%) in the first 3 rats, and amounted to 17% in the fourth. A statistically significant average loss of bone (16%) was found in the 10 rats in the main study when comparing the weights of papers at days 0 and 63.
Language
  • English
Open access status
closed
Identifiers
Persistent URL
https://sonar.ch/global/documents/5175
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