Journal article
Synthetic biology-application-oriented cell engineering.
- Xie M Department of Biosystems Science and Engineering, ETH Zurich, Mattenstrasse 26, CH-4058 Basel, Switzerland.
- Haellman V Department of Biosystems Science and Engineering, ETH Zurich, Mattenstrasse 26, CH-4058 Basel, Switzerland.
- Fussenegger M Department of Biosystems Science and Engineering, ETH Zurich, Mattenstrasse 26, CH-4058 Basel, Switzerland; University of Basel, Faculty of Science, Mattenstrasse 26, CH-4058 Basel, Switzerland. Electronic address: fussenegger@bsse.ethz.ch.
- 2016-05-03
Published in:
- Current opinion in biotechnology. - 2016
English
Synthetic biology applies engineering principles to biological systems and reprograms living cells to perform novel and improved functions. In this review, we first provide an update of common tools and design principles that enable user-defined control of mammalian cell activities with spatiotemporal precision. Next, we demonstrate some examples of how engineered mammalian cells can be developed towards biomedical solutions in the context of real-world problems.
- Language
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- English
- Open access status
- closed
- Identifiers
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- DOI 10.1016/j.copbio.2016.04.005
- PMID 27135809
- Persistent URL
- https://sonar.ch/global/documents/52192
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